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Protein posttranslational modifications in health and diseases: Functions, regulatory mechanisms, and therapeutic implications
Q Zhong, X **ao, Y Qiu, Z Xu, C Chen, B Chong… - MedComm, 2023 - Wiley Online Library
Protein posttranslational modifications (PTMs) refer to the breaking or generation of covalent
bonds on the backbones or amino acid side chains of proteins and expand the diversity of …
bonds on the backbones or amino acid side chains of proteins and expand the diversity of …
Expanding the frontiers of guardian antioxidant selenoproteins in cardiovascular pathophysiology
Significance: Physiological levels of reactive oxygen and nitrogen species (ROS/RNS)
function as fundamental messengers for many cellular and developmental processes in the …
function as fundamental messengers for many cellular and developmental processes in the …
[HTML][HTML] Role of oxidative stress in the pathogenesis of atherothrombotic diseases
Oxidative stress is generated by the imbalance between reactive oxygen species (ROS)
formation and antioxidant scavenger system's activity. Increased ROS, such as superoxide …
formation and antioxidant scavenger system's activity. Increased ROS, such as superoxide …
Activation of Nrf2 signaling: A key molecular mechanism of protection against cardiovascular diseases by natural products
X Wu, J Wei, Y Yi, Q Gong, J Gao - Frontiers in pharmacology, 2022 - frontiersin.org
Cardiovascular diseases (CVD) are a group of cardiac and vascular disorders including
myocardial ischemia, congenital heart disease, heart failure, hypertension, atherosclerosis …
myocardial ischemia, congenital heart disease, heart failure, hypertension, atherosclerosis …
Enzyme-responsive COF-based thiol-targeting nanoinhibitor for curing bacterial infections
X Wang, B Sun, Z Ye, W Zhang, W Xu… - … Applied Materials & …, 2022 - ACS Publications
Pathogen infections impose severe challenges in clinical practice, especially for patients
infected with antibiotic-resistant microbes. The thioredoxin (Trx) system in Gram-positive …
infected with antibiotic-resistant microbes. The thioredoxin (Trx) system in Gram-positive …
Sulfur-based fluorescent probes for biological analysis: A review
G Hu, H Xu, J Fang - Talanta, 2024 - Elsevier
The widespread adoption of small-molecule fluorescence detection methodologies in
scientific research and industrial contexts can be ascribed to their inherent merits, including …
scientific research and industrial contexts can be ascribed to their inherent merits, including …
Fibroblast growth factor 18 alleviates stress-induced pathological cardiac hypertrophy in male mice
G Chen, N An, J Shen, H Chen, Y Chen, J Sun… - Nature …, 2023 - nature.com
Abstract Fibroblast growth factor-18 (FGF18) has diverse organ development and damage
repair roles. However, its role in cardiac homeostasis following hypertrophic stimulation …
repair roles. However, its role in cardiac homeostasis following hypertrophic stimulation …
Importance of mitochondria in cardiac pathologies: focus on uncoupling proteins and monoamine oxidases
R Schulz, KD Schlüter - International journal of molecular sciences, 2023 - mdpi.com
On the one hand, reactive oxygen species (ROS) are involved in the onset and progression
of a wide array of diseases. On the other hand, these are a part of signaling pathways …
of a wide array of diseases. On the other hand, these are a part of signaling pathways …
[HTML][HTML] Disulfide stress and its role in cardiovascular diseases
S Qian, G Chen, R Li, Y Ma, L Pan, X Wang, X Wang - Redox Biology, 2024 - Elsevier
Cardiovascular disease (CVD) is one of the leading causes of mortality in humans, and
oxidative stress plays a pivotal role in disease progression. This phenomenon typically …
oxidative stress plays a pivotal role in disease progression. This phenomenon typically …
Diosmetin protects against cardiac hypertrophy via p62/Keap1/Nrf2 signaling pathway
Y Guo, D Li, X Cen, H Qiu, Y Ma, Y Liu… - Oxidative Medicine …, 2022 - Wiley Online Library
An important pathophysiological consequence of pressure overload‐induced cardiac
hypertrophy is adverse cardiac remodeling, including structural changes in cardiomyocytes …
hypertrophy is adverse cardiac remodeling, including structural changes in cardiomyocytes …