IL-1 receptor-associated kinase family proteins: An overview of their role in liver disease

Z Wang, S Gao, X Gou, F Qiu, Q Feng - European Journal of Pharmacology, 2024 - Elsevier
Abstract 1 The interleukin-1 receptor-associated kinase (IRAK) family is a group of serine-
threonine kinases that regulates various cellular processes via toll-like receptor …

Liver cancer wars: plant-derived polyphenols strike back

C Niu, J Zhang, PI Okolo 3rd - Medical Oncology, 2024 - Springer
Liver cancer currently represents the leading cause of cancer-related death worldwide. The
majority of liver cancer arises in the context of chronic inflammation and cirrhosis. Surgery …

Key oncogenes and candidate drugs for hepatitis-B-driven hepatocellular carcinoma progression

L Ruan, N Fang, X Zhao, W Chen, Z Wu, X Wu - Discover Oncology, 2025 - Springer
Background This study aimed to uncover the key hepatitis-B (HB)-related liver cancer (LC)
promoting genes, and clarity their interrelationships, enrichments, impacts on LC immune …

A MR-PheWAS and bidirectional Mendelian randomization study: Exploring for causal relationships of pancreatic cancer

A Guan, Z Li, X Guo - Medicine, 2024 - journals.lww.com
It is unknown what causes pancreatic cancer. We conducted a phenome-wide Mendelian
randomization analysis (MR-pheWAS), a bidirectional Mendelian study, and a systematic …

Identification of key exosomes-related genes in hepatitis B virus-related hepatocellular carcinoma

Z Wang, J Lu, X Liu, J Liu, J Li - Technology and Health …, 2024 - journals.sagepub.com
<? show [AQ ID= GQ4]?><? show [AQ ID= GQ6 POS= 12pt]?> One of the primary risk factors
for hepatocellular carcinoma (HCC) is the hepatitis B virus (HBV). Exosomes have a …

Pollutants in Microenvironmental Cellular Interactions During Liver Inflammation Cancer Transition and the Application of Multi-Omics Analysis

Y Jian, Y Li, Y Zhou, W Mu - Toxics, 2025 - mdpi.com
This study categorizes pollutant-induced inflammation–cancer transition into three stages:
non-alcoholic faty liver disease (NAFLD), liver fibrosis, and hepatocellular carcinoma (HCC) …