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Non-coding RNA in the wiring and remodeling of neural circuits
M Soutschek, G Schratt - Neuron, 2023 - cell.com
The brain constantly adapts to changes in the environment, a capability that underlies
memory and behavior. Long-term adaptations require the remodeling of neural circuits that …
memory and behavior. Long-term adaptations require the remodeling of neural circuits that …
Epigenetic mechanisms underlying sex differences in the brain and behavior
M Kundakovic, M Tickerhoof - Trends in neurosciences, 2024 - cell.com
Sex differences are found across brain regions, behaviors, and brain diseases. Sexual
differentiation of the brain is initiated prenatally but it continues throughout life, as a result of …
differentiation of the brain is initiated prenatally but it continues throughout life, as a result of …
Sex differences in stress response: Classical mechanisms and beyond
Neuropsychiatric disorders, which are associated with stress hormone dysregulation, occur
at different rates in men and women. Moreover, nowadays, preclinical and clinical evidence …
at different rates in men and women. Moreover, nowadays, preclinical and clinical evidence …
Epigenetic mechanisms of rapid-acting antidepressants
Abstract Background Rapid-acting antidepressants (RAADs), including dissociative
anesthetics, psychedelics, and empathogens, elicit rapid and sustained therapeutic …
anesthetics, psychedelics, and empathogens, elicit rapid and sustained therapeutic …
Noncoding RNAs: emerging regulators of behavioral complexity
The mammalian genome encodes thousands of non− coding RNAs (ncRNAs), ranging in
size from about 20 nucleotides (microRNAs or miRNAs) to kilobases (long non− coding …
size from about 20 nucleotides (microRNAs or miRNAs) to kilobases (long non− coding …
SNORA69 is up-regulated in the lateral habenula of individuals with major depressive disorder
Major depressive disorder (MDD) is a complex and potentially debilitating illness whose
etiology and pathology remains unclear. Non-coding RNAs have been implicated in MDD …
etiology and pathology remains unclear. Non-coding RNAs have been implicated in MDD …
Epigenetic mechanisms in depression: implications for pathogenesis and treatment
HS Chen, F Wang, JG Chen - Current Opinion in Neurobiology, 2024 - Elsevier
The risk of depression is influenced by both genetic and environmental factors. It has been
suggested that epigenetic mechanisms may mediate the risk of depression following …
suggested that epigenetic mechanisms may mediate the risk of depression following …
Male and female behavioral variability and morphine response in C57BL/6J, DBA/2J, and their BXD progeny following chronic stress exposure
Drug addiction is a multifactorial syndrome in which genetic predispositions and exposure to
environmental stressors constitute major risk factors for the early onset, escalation, and …
environmental stressors constitute major risk factors for the early onset, escalation, and …
Identification of potential biomarkers for major depressive disorder: based on integrated bioinformatics and clinical validation
X Zhong, Y Chen, W Chen, Y Liu, S Gui, J Pu… - Molecular …, 2024 - Springer
Major depressive disorder (MDD) is a severe mental illness characterized by a lack of
objective biomarkers. Mounting evidence suggests there are extensive transcriptional …
objective biomarkers. Mounting evidence suggests there are extensive transcriptional …
Unique spatially and temporary-regulated/sex-specific expression of a long ncRNA, Nb-1, suggesting its pleiotropic functions associated with honey bee lifecycle
H Tadano, H Kohno, H Takeuchi, T Kubo - Scientific Reports, 2024 - nature.com
Honey bees are social insects, and each colony member has unique morphological and
physiological traits associated with their social tasks. Previously, we identified a long non …
physiological traits associated with their social tasks. Previously, we identified a long non …