The role of meat in foodborne disease: Is there a coming revolution in risk assessment and management?

N Fegan, I Jenson - Meat science, 2018 - Elsevier
Meat has featured prominently as a source of foodborne disease and a public health
concern. For about the past 20 years the risk management paradigm has dominated …

Dose–response and transmission: the nexus between reservoir hosts, environment and recipient hosts

TJ Lunn, O Restif, AJ Peel… - … of the Royal …, 2019 - royalsocietypublishing.org
Dose is the nexus between exposure and all upstream processes that determine pathogen
pressure, and is thereby an important element underlying disease dynamics. Understanding …

In defence of Bacillus thuringiensis, the safest and most successful microbial insecticide available to humanity—a response to EFSA

B Raymond, BA Federici - FEMS microbiology ecology, 2017 - academic.oup.com
The Bacillus cereus group contains vertebrate pathogens such as B. anthracis and B. cereus
and the invertebrate pathogen B. thuringiensis (Bt). Microbial biopesticides based on Bt are …

A novel metalloproteinase virulence factor is involved in Bacillus thuringiensis pathogenesis in nematodes and insects

D Peng, J Lin, Q Huang, W Zheng, G Liu… - Environmental …, 2016 - Wiley Online Library
The Gram‐positive soil bacterium B acillus thuringiensis has been developed as the leading
microbial insecticide for years. The pathogenesis of B. thuringiensis requires common …

Selecting for infectivity across metapopulations can increase virulence in the social microbe Bacillus thuringiensis

T Dimitriu, W Souissi, P Morwool, A Darby… - Evolutionary …, 2023 - Wiley Online Library
Passage experiments that sequentially infect hosts with parasites have long been used to
manipulate virulence. However, for many invertebrate pathogens, passage has been …

Passage and the evolution of virulence in invertebrate pathogens: Fundamental and applied perspectives

B Raymond, Z Erdos - Journal of Invertebrate Pathology, 2022 - Elsevier
Understanding the ecological and genetic factors that determine the evolution of virulence
has broad value for invertebrate pathology. In addition to hel** us understand the …

Combining the high‐dose/refuge strategy and self‐limiting transgenic insects in resistance management—A test in experimental mesocosms

L Zhou, N Alphey, AS Walker, LM Travers… - Evolutionary …, 2018 - Wiley Online Library
The high‐dose/refuge strategy has been the primary approach for resistance management
in transgenic crops engineered with Bacillus thuringiensis toxins. However, there are …

Dose-dependent interaction of parasites with tiers of host defense predicts “wormholes” that prolong infection at intermediate inoculum sizes

AL Graham, RR Regoes - PLOS Computational Biology, 2024 - journals.plos.org
Immune responses are induced by parasite exposure and can in turn reduce parasite
burden. Despite such apparently simple rules of engagement, key drivers of within-host …

Shifts along the parasite–mutualist continuum are opposed by fundamental trade-offs

AC Matthews, L Mikonranta… - Proceedings of the …, 2019 - royalsocietypublishing.org
Theory suggests that symbionts can readily evolve more parasitic or mutualistic strategies
with respect to hosts. However, many symbionts have stable interactions with hosts that …

Making pathogens sociable: The emergence of high relatedness through limited host invasibility

E Van Leeuwen, S O'Neill, A Matthews… - The ISME …, 2015 - academic.oup.com
Cooperation depends upon high relatedness, the high genetic similarity of interacting
partners relative to the wider population. For pathogenic bacteria, which show diverse …