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BDNF as a promising therapeutic agent in Parkinson's disease
E Palasz, A Wysocka, A Gasiorowska… - International journal of …, 2020 - mdpi.com
Brain-derived neurotrophic factor (BDNF) promotes neuroprotection and neuroregeneration.
In animal models of Parkinson's disease (PD), BDNF enhances the survival of dopaminergic …
In animal models of Parkinson's disease (PD), BDNF enhances the survival of dopaminergic …
Physical exercise as an epigenetic modulator of brain plasticity and cognition
A large amount of evidence has demonstrated the power of exercise to support cognitive
function, the effects of which can last for considerable time. An emerging line of scientific …
function, the effects of which can last for considerable time. An emerging line of scientific …
BDNF and synaptic plasticity, cognitive function, and dysfunction
B Lu, G Nagappan, Y Lu - Neurotrophic factors, 2014 - Springer
Among all neurotrophins, brain-derived neurotrophic factor (BDNF) stands out for its high
level of expression in the brain and its potent effects on synapses. It is now widely accepted …
level of expression in the brain and its potent effects on synapses. It is now widely accepted …
BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases
B Lu, G Nagappan, X Guan, PJ Nathan… - Nature Reviews …, 2013 - nature.com
Increasing evidence suggests that synaptic dysfunction is a key pathophysiological hallmark
in neurodegenerative disorders, including Alzheimer's disease. Understanding the role of …
in neurodegenerative disorders, including Alzheimer's disease. Understanding the role of …
BDNF-induced local protein synthesis and synaptic plasticity
G Leal, D Comprido, CB Duarte - Neuropharmacology, 2014 - Elsevier
Brain-derived neurotrophic factor (BDNF) is an important regulator of synaptic transmission
and long-term potentiation (LTP) in the hippocampus and in other brain regions, playing a …
and long-term potentiation (LTP) in the hippocampus and in other brain regions, playing a …
Exercise influence on the microbiome–gut–brain axis
A Dalton, C Mermier, M Zuhl - Gut microbes, 2019 - Taylor & Francis
The microbiome in the gut is a diverse environment, housing the majority of our bacterial
microbes. This microecosystem has a symbiotic relationship with the surrounding …
microbes. This microecosystem has a symbiotic relationship with the surrounding …
Regulation of hippocampal synaptic plasticity by BDNF
G Leal, PM Afonso, IL Salazar, CB Duarte - Brain research, 2015 - Elsevier
The neurotrophin brain-derived neurotrophic factor (BDNF) has emerged as a major
regulator of activity-dependent plasticity at excitatory synapses in the mammalian central …
regulator of activity-dependent plasticity at excitatory synapses in the mammalian central …
Oxidative stress in cognitive and epigenetic aging: a retrospective glance
A Kandlur, K Satyamoorthy… - Frontiers in molecular …, 2020 - frontiersin.org
Brain aging is the critical and common factor among several neurodegenerative disorders
and dementia. Cellular, biochemical and molecular studies have shown intimate links …
and dementia. Cellular, biochemical and molecular studies have shown intimate links …
The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
Brain-derived neurotrophic factor (BDNF) modulates hippocampal plasticity and
hippocampal-dependent memory in cell models and in animals. We examined the effects of …
hippocampal-dependent memory in cell models and in animals. We examined the effects of …
Brain foods: the effects of nutrients on brain function
F Gómez-Pinilla - Nature reviews neuroscience, 2008 - nature.com
It has long been suspected that the relative abundance of specific nutrients can affect
cognitive processes and emotions. Newly described influences of dietary factors on …
cognitive processes and emotions. Newly described influences of dietary factors on …