The COVID-19 pandemic galvanized the field of virus genomic surveillance, demonstrating
its utility for public health. Now, we must harness the momentum that led to increased …

Over the past decade, a genomics revolution, made possible through the development of
high-throughput sequencing, has triggered considerable progress in the study of ancient …

Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in
Manaus, Brazil, resurged in late 2020 despite previously high levels of infection. Genome …

How viruses evolve within hosts can dictate infection outcomes; however, reconstructing this
process is challenging. We evaluate our multiplexed amplicon approach, PrimalSeq, to …

Genome sequencing has become a powerful tool for studying emerging infectious diseases;
however, genome sequencing directly from clinical samples (ie, without isolation and …

In conventional photodynamic therapy (PDT), reactive oxygen species are produced to kill
cancer cells based on type-I and type-II mechanisms, and the sensitization of …

The transmission of pathogens from wild animals to humans is called “zoonotic spillover”.
Most human infectious diseases (60-75%) are derived from pathogens that originally …

Although the recent Zika virus (ZIKV) epidemic in the Americas and its link to birth defects
have attracted a great deal of attention,, much remains unknown about ZIKV disease …

Zika virus (ZIKV) is causing an unprecedented epidemic linked to severe congenital
abnormalities,. In July 2016, mosquito-borne ZIKV transmission was reported in the …

Next generation sequencing (NGS) combined with bioinformatics has successfully been
used in a vast array of analyses for infectious disease research of public health relevance …