Super-resolution microscopy demystified

L Schermelleh, A Ferrand, T Huser, C Eggeling… - Nature cell …, 2019 - nature.com
Super-resolution microscopy (SRM) bypasses the diffraction limit, a physical barrier that
restricts the optical resolution to roughly 250 nm and was previously thought to be …

Visualizing and discovering cellular structures with super-resolution microscopy

YM Sigal, R Zhou, X Zhuang - Science, 2018 - science.org
Super-resolution microscopy has overcome a long-held resolution barrier—the diffraction
limit—in light microscopy and enabled visualization of previously invisible molecular details …

Once and only once: mechanisms of centriole duplication and their deregulation in disease

EA Nigg, AJ Holland - Nature reviews Molecular cell biology, 2018 - nature.com
Centrioles are conserved microtubule-based organelles that form the core of the centrosome
and act as templates for the formation of cilia and flagella. Centrioles have important roles in …

Centrosome function and assembly in animal cells

PT Conduit, A Wainman, JW Raff - Nature reviews Molecular cell …, 2015 - nature.com
It has become clear that the role of centrosomes extends well beyond that of important
microtubule organizers. There is increasing evidence that they also function as coordination …

Mechanism and regulation of centriole and cilium biogenesis

DK Breslow, AJ Holland - Annual review of biochemistry, 2019 - annualreviews.org
The centriole is an ancient microtubule-based organelle with a conserved nine-fold
symmetry. Centrioles form the core of centrosomes, which organize the interphase …

Precisely and accurately localizing single emitters in fluorescence microscopy

H Deschout, FC Zanacchi, M Mlodzianoski, A Diaspro… - Nature …, 2014 - nature.com
Methods based on single-molecule localization and photophysics have brought nanoscale
imaging with visible light into reach. This has enabled single-particle tracking applications …

Structural and functional photoacoustic molecular tomography aided by emerging contrast agents

L Nie, X Chen - Chemical Society Reviews, 2014 - pubs.rsc.org
Photoacoustic tomography (PAT) can offer structural, functional and molecular contrasts at
scalable observation level. By ultrasonically overcoming the strong optical scattering, this …

Super-resolution microscopy: from single molecules to supramolecular assemblies

AM Sydor, KJ Czymmek, EM Puchner, V Mennella - Trends in cell biology, 2015 - cell.com
Super-resolution microscopy (SRM) methods have allowed scientists to exceed the
diffraction limit of light, enabling the discovery and investigation of cellular structures at the …

Microtubule-organizing centers

J Wu, A Akhmanova - Annual review of cell and developmental …, 2017 - annualreviews.org
The organization of microtubule networks is crucial for controlling chromosome segregation
during cell division, for positioning and transport of different organelles, and for cell polarity …