Extracellular vesicles (EVs) are complex lipid membrane vehicles with variable expressions
of molecular cargo, composed of diverse subpopulations that participate in the intercellular …

Flow cytometry (FCM) is a sophisticated technique that works on the principle of light
scattering and fluorescence emission by the specific fluorescent probe-labeled cells as they …

Although mutations in mitochondrial-associated genes are linked to inflammation and
susceptibility to infection, their mechanistic contributions to immune outcomes remain ill …

Mitochondria have been primarily considered intracellular organelles that are responsible
for generating energy for cell survival. However, accumulating evidence suggests that …

An overview of the sperm metabolism is presented; using the stallion as a model we review
glycolysis, Krebs Cycle and oxidative phosphorylation, paying special attention to the …

Stem cells and the niche in which they reside feature a complex microenvironment with
tightly regulated homeostasis, cell-cell interactions and dynamic regulation of metabolism. A …

Mitochondria tailor their morphology to execute their specialized functions in different cell
types and/or different environments. During spermatogenesis, mitochondria undergo …

Mitochondria are key bioenergetic organelles involved in many biosynthetic and signaling
pathways. However, their differential contribution to specific functions of cells within complex …

Mitochondria are ancient endosymbiotic double membrane organelles that support a wide
range of eukaryotic cell functions through energy, metabolism, and cellular control. There …

Therapeutic targeting of leukemic stem cells is widely studied to control leukemia. An
emerging approach gaining popularity is altering metabolism as a potential therapeutic …