G protein–coupled receptor kinases (GRKs) constitute a family of six mammalian
serine/threonine protein kinases that phosphorylate agonist-bound, or activated, G protein …

G protein-coupled receptor (GPCR) kinases (GRKs) are best known for their role in
homologous desensitization of GPCRs. GRKs phosphorylate activated receptors and …

The Arabidopsis thaliana SOS2 and SOS3 genes are required for intracellular Na+ and K+
homeostasis and plant tolerance to high Na+ and low K+ environments. SOS3 is an EF hand …

▪ Abstract G protein–coupled receptors (GPRs) play a key role in controlling hormonal
regulation of numerous second-messenger pathways. However, following agonist activation …

This review is provided in recognition of the extensive contributions of Dr. Robert J.
Lefkowitz to the G protein-coupled receptor (GPCR) field and to celebrate his 75th birthday …

Of the many forms of GPCR1 regulation none has received as much attention as the process
of receptor desensitization, ie the waning responsiveness of the receptors in the face of …

In neurons, intracellular calcium signals have crucial roles in activating neurotransmitter
release and in triggering alterations in neuronal function. Calmodulin has been widely …

When light is absorbed within the outer segment of a vertebrate photoreceptor, the
conformation of the photopigment rhodopsin is altered to produce an activated photoproduct …

The basis of the duplex theory of vision is examined in view of the dazzling array of data on
visual pigment sequences and the pigments they form, on the microspectrophotometry …

This book provides the reader with an account of some of the experimental evidence on
which our present knowledge is based. The third edition of this highly successful book has …