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Utility of B-factors in protein science: interpreting rigidity, flexibility, and internal motion and engineering thermostability
Z Sun, Q Liu, G Qu, Y Feng, MT Reetz - Chemical reviews, 2019 - ACS Publications
The term B-factor, sometimes called the Debye–Waller factor, temperature factor, or atomic
displacement parameter, is used in protein crystallography to describe the attenuation of X …
displacement parameter, is used in protein crystallography to describe the attenuation of X …
Biosynthesis of fungal meroterpenoids
Covering: up to September 2015 Meroterpenoids are hybrid natural products that partially
originate from the terpenoid pathway. The meroterpenoids derived from fungi display quite …
originate from the terpenoid pathway. The meroterpenoids derived from fungi display quite …
[KNJIGA][B] Hydrolases in organic synthesis: regio-and stereoselective biotransformations
UT Bornscheuer, RJ Kazlauskas - 2006 - books.google.com
From reviews to the first edtion:" Bornscheuer and Kazlauskas have set out, and succeeded,
in producing a definitive manual on hydrolytic enzymes (especially lipases, esterases, and …
in producing a definitive manual on hydrolytic enzymes (especially lipases, esterases, and …
Computationally designed libraries for rapid enzyme stabilization
The ability to engineer enzymes and other proteins to any desired stability would have wide-
ranging applications. Here, we demonstrate that computational design of a library with …
ranging applications. Here, we demonstrate that computational design of a library with …
Epoxide hydrolases: their roles and interactions with lipid metabolism
The epoxide hydrolases (EHs) are enzymes present in all living organisms, which transform
epoxide containing lipids by the addition of water. In plants and animals, many of these lipid …
epoxide containing lipids by the addition of water. In plants and animals, many of these lipid …
Epoxide hydrolases: mechanisms, inhibitor designs, and biological roles
C Morisseau, BD Hammock - Annu. Rev. Pharmacol. Toxicol., 2005 - annualreviews.org
▪ Abstract Organisms are exposed to epoxide-containing compounds from both exogenous
and endogenous sources. In mammals, the hydration of these compounds by various …
and endogenous sources. In mammals, the hydration of these compounds by various …
Enzymes from extreme environments and their industrial applications
JA Littlechild - Frontiers in bioengineering and biotechnology, 2015 - frontiersin.org
This article will discuss the importance of specific extremophilic enzymes for applications in
industrial biotechnology. It will specifically address those enzymes that have applications in …
industrial biotechnology. It will specifically address those enzymes that have applications in …
Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A
The major facilitator superfamily (MFS) is the largest family of secondary active transporters
and is present in all life kingdoms. Detailed structural basis of the substrate transport and …
and is present in all life kingdoms. Detailed structural basis of the substrate transport and …
Mammalian epoxide hydrolases in xenobiotic metabolism and signalling
M Decker, M Arand, A Cronin - Archives of toxicology, 2009 - Springer
Epoxide hydrolases catalyse the hydrolysis of electrophilic—and therefore potentially
genotoxic—epoxides to the corresponding less reactive vicinal diols, which explains the …
genotoxic—epoxides to the corresponding less reactive vicinal diols, which explains the …
Enantioselective enzymes by computational design and in silico screening
Computational enzyme design holds great promise for providing new biocatalysts for
synthetic chemistry. A strategy to design small mutant libraries of complementary …
synthetic chemistry. A strategy to design small mutant libraries of complementary …