Tomographic phase microscopy: principles and applications in bioimaging

D **, R Zhou, Z Yaqoob, PTC So - JOSA B, 2017 - opg.optica.org
Tomographic phase microscopy (TPM) is an emerging optical microscopic technique for
bioimaging. TPM uses digital holographic measurements of complex scattered fields to …

Holographic tomography: techniques and biomedical applications

V Balasubramani, A Kuś, HY Tu, CJ Cheng… - Applied Optics, 2021 - opg.optica.org
Holographic tomography (HT) is an advanced label-free optical microscopic imaging
method used for biological studies. HT uses digital holographic microscopy to record the …

Phase imaging with computational specificity (PICS) for measuring dry mass changes in sub-cellular compartments

ME Kandel, YR He, YJ Lee, THY Chen… - Nature …, 2020 - nature.com
Due to its specificity, fluorescence microscopy has become a quintessential imaging tool in
cell biology. However, photobleaching, phototoxicity, and related artifacts continue to limit …

Optical diffraction tomography techniques for the study of cell pathophysiology

K Kim, J Yoon, S Shin, SY Lee, SA Yang… - Journal of Biomedical …, 2016 - cyberleninka.ru
Three-dimensional imaging of biological cells is crucial for the investigation of cell biology,
providing valuable information to reveal the mechanisms behind pathophysiology of cells …

Quantitative phase imaging for medical diagnosis

H Majeed, S Sridharan, M Mir, L Ma, E Min… - Journal of …, 2017 - Wiley Online Library
Optical microscopy is an indispensable diagnostic tool in modern healthcare. As a prime
example, pathologists rely exclusively on light microscopy to investigate tissue morphology …

Three-dimensional label-free imaging and quantification of lipid droplets in live hepatocytes

K Kim, SE Lee, J Yoon, JH Heo, C Choi, YK Park - Scientific reports, 2016 - nature.com
Lipid droplets (LDs) are subcellular organelles with important roles in lipid storage and
metabolism and involved in various diseases including cancer, obesity, and diabetes …

Time-multiplexed structured illumination using a DMD for optical diffraction tomography

KR Lee, K Kim, G Kim, S Shin, YK Park - Optics letters, 2017 - opg.optica.org
We present a time-multiplexing structured illumination control technique for optical diffraction
tomography (ODT). Instead of tilting the angle of illumination, time-multiplexed sinusoidal …

Identification of non-activated lymphocytes using three-dimensional refractive index tomography and machine learning

J Yoon, YJ Jo, M Kim, K Kim, SY Lee, SJ Kang… - Scientific reports, 2017 - nature.com
Identification of lymphocyte cell types are crucial for understanding their pathophysiological
roles in human diseases. Current methods for discriminating lymphocyte cell types primarily …

Label-free characterization of white blood cells by measuring 3D refractive index maps

J Yoon, K Kim, HJ Park, C Choi, S Jang… - Biomedical optics …, 2015 - opg.optica.org
The characterization of white blood cells (WBCs) is crucial for blood analyses and disease
diagnoses. However, current standard techniques rely on cell labeling, a process which …

Refractive index tomograms and dynamic membrane fluctuations of red blood cells from patients with diabetes mellitus

SY Lee, HJ Park, S Jang, Y Park - Biophysical Journal, 2017 - cell.com
218a Monday, February 13, 2017 laser interferometric techniques, the three-dimensional
refractive index maps and dynamic membrane fluctuations are quantitatively and non …