Preeclampsia is one of the “great obstetrical syndromes” in which multiple and sometimes
overlap** pathologic processes activate a common pathway consisting of endothelial cell …

Abstract Background In Europe cardiovascular disease (CVD) is responsible for 3.9 million
deaths (45% of deaths), being ischaemic heart disease, stroke, hypertension (leading to …

Atherosclerosis is central to the pathology of cardiovascular diseases, a group of diseases in
which arteries become occluded with atheromas that may rupture, leading to different …

Atherosclerotic cardiovascular disease (ACVD) is an inflammatory disease of the coronary
arteries associated with atheroma formation, which can cause disability and often death …

Background Nod‐like receptor family pyrin domain‐containing protein‐3 (NLRP3) complex
inflammasome has potentially been shown to play an important role in the development of …

Cardiovascular diseases still account for the majority of deaths worldwide, although
significant improvements in survival, after being affected by cardiovascular disease, have …

Background Fusobacterium nucleatum (F. nucleatum) is an anaerobic oral commensal and
the major coaggregation bridge organism linking early and late colonisers. In recent years, a …

Background Dental calculus, calcified oral plaque biofilm, contains microbial and host
biomolecules that can be used to study historic microbiome communities and host …

Periodontal disease is a disease of tooth-supporting tissues. It is a chronic disease with
inflammatory nature and infectious etiology produced by a dysbiotic subgingival microbiota …

Integrins are cell surface receptors that traditionally mediate cell-to-extracellular matrix and
cell-to-cell adhesion. They can, however, also bind a large repertoire of other molecules …