Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics

Y Duan, K Gong, S Xu, F Zhang, X Meng… - Signal Transduction and …, 2022 - nature.com
Disturbed cholesterol homeostasis plays critical roles in the development of multiple
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …

Shortening synthetic routes to small molecule active pharmaceutical ingredients employing biocatalytic methods

S Simić, E Zukić, L Schmermund, K Faber… - Chemical …, 2021 - ACS Publications
Biocatalysis, using enzymes for organic synthesis, has emerged as powerful tool for the
synthesis of active pharmaceutical ingredients (APIs). The first industrial biocatalytic …

2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk The Task Force for the management of …

F Mach, C Baigent, AL Catapano… - European heart …, 2020 - academic.oup.com
version of the Guidelines, which is freely available via the ESC and EAS websites and
hosted on their journals' websites (EHJ and Atherosclerosis Journal). The National Cardiac …

2023 Chinese guideline for lipid management

JJ Li, SP Zhao, D Zhao, GP Lu, DQ Peng… - Frontiers in …, 2023 - frontiersin.org
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death among urban
and rural residents in China, and elevated low-density lipoprotein cholesterol (LDL-C) is a …

Steatotic liver disease: pathophysiology and emerging pharmacotherapies

M Kokkorakis, E Muzurović, Š Volčanšek… - Pharmacological …, 2024 - Elsevier
Steatotic liver disease (SLD) displays a dynamic and complex disease phenotype.
Consequently, the metabolic dysfunction-associated steatotic liver disease …

Combating physical inactivity during the COVID-19 pandemic

AJ Pinto, DW Dunstan, N Owen, E Bonfá… - Nature Reviews …, 2020 - nature.com
Physical inactivity is common during periods of self-isolation, but for patients with rheumatic
diseases, there are crucial benefits to be gained from maintaining an active lifestyle …

Dyslipidaemia in nephrotic syndrome: mechanisms and treatment

S Agrawal, JJ Zaritsky, A Fornoni… - Nature Reviews …, 2018 - nature.com
Nephrotic syndrome is a highly prevalent disease that is associated with high morbidity
despite notable advances in its treatment. Many of the complications of nephrotic syndrome …

Atherosclerotic cardiovascular disease prevention in rheumatoid arthritis

AG Semb, E Ikdahl, G Wibetoe, C Crowson… - Nature Reviews …, 2020 - nature.com
Patients with rheumatoid arthritis (RA) are at high risk of develo** cardiovascular disease
(CVD). Inflammation has a pivotal role in the pathogenesis of CVD. RA is an inflammatory …

American Association of Clinical Endocrinologists and American College of Endocrinology guidelines for management of dyslipidemia and prevention of …

PS Jellinger, Y Handelsman, PD Rosenblit… - Endocrine Practice, 2017 - Elsevier
Objective The development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and American College of Endocrinology …

[PDF][PDF] 2019 ESC/EAS guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk

ESCNC Societies, F Mach, C Baigent… - …, 2019 - researchportal.helsinki.fi
2019 ESC/EAS guidelines for the management of dyslipidaemias : Lipid modification to reduce
cardiovascular risk Task Force Membe Page 1 https://helda.helsinki.fi 2019 ESC/EAS guidelines for …