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Neural circuits for the adaptive regulation of fear and extinction memory
The regulation of fear memories is critical for adaptive behaviors and dysregulation of these
processes is implicated in trauma-and stress-related disorders. Treatments for these …
processes is implicated in trauma-and stress-related disorders. Treatments for these …
[HTML][HTML] In relentless pursuit of the white whale: a role for the ventral midline thalamus in behavioral flexibility and adaption?
E Panzer, I Guimares-Olmo, AP de Vasconcelos… - Neuroscience & …, 2024 - Elsevier
The reuniens (Re) nucleus is located in the ventral midline thalamus. It has fostered
increasing interest, not only for its participation in a variety of cognitive functions (eg, spatial …
increasing interest, not only for its participation in a variety of cognitive functions (eg, spatial …
Periplaneta Americana (L.) extract activates the ERK/CREB/BDNF pathway to promote post-stroke neuroregeneration and recovery of neurological functions in rats
J Rao, H Li, H Zhang, X **ang, X Ding, L Li… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Periplaneta americana (L.)(PA) has been used in
traditional Chinese medicine for thousands of years for the effect of invigorating blood …
traditional Chinese medicine for thousands of years for the effect of invigorating blood …
Chemogenetic inactivation of the nucleus reuniens and its projections to the orbital cortex produce deficits on discrete measures of behavioral flexibility in the …
The nucleus reuniens (RE) of the ventral midline thalamus is a critical node in the
communication between the orbitomedial prefrontal cortex (OFC) and the hippocampus …
communication between the orbitomedial prefrontal cortex (OFC) and the hippocampus …
An ultra-short-acting benzodiazepine in thalamic nucleus reuniens undermines fear extinction via intermediation of hippocamposeptal circuits
H Cheung, TZ Yu, X Yi, YJ Wu, Q Wang, X Gu… - Communications …, 2024 - nature.com
Benzodiazepines, commonly used for anxiolytics, hinder conditioned fear extinction, and the
underlying circuit mechanisms are unclear. Utilizing remimazolam, an ultra-short-acting …
underlying circuit mechanisms are unclear. Utilizing remimazolam, an ultra-short-acting …
Diencephalic modulation of the hippocampus in affective and cognitive behavior
Highlights•The two major diencephalic inputs to the hippocampus are the nucleus reuniens
and the supramammillary nucleus.•The nucleus reuniens serves a critical role in spatial …
and the supramammillary nucleus.•The nucleus reuniens serves a critical role in spatial …
[HTML][HTML] Cognitive dysfunction in early experimental metabolic dysfunction-associated steatotic liver disease is associated with systemic inflammation and …
Background & Aims Cognitive dysfunction is an increasingly recognised manifestation of
metabolic dysfunction-associated steatotic liver disease (MASLD), but the mechanistic link …
metabolic dysfunction-associated steatotic liver disease (MASLD), but the mechanistic link …
Virtual reality modulating dynamics of neuroplasticity: Innovations in neuro-motor rehabilitation
NL Wankhede, S Koppula, S Ballal, H Doshi… - Neuroscience, 2025 - Elsevier
Virtual reality (VR) technology has emerged as a ground-breaking tool in neuroscience,
revolutionizing our understanding of neuroplasticity and its implications for neurological …
revolutionizing our understanding of neuroplasticity and its implications for neurological …
CA1 engram cell dynamics before and after learning
A fundamental question in neuroscience is how memory formation shapes brain activity at
the level of populations of neurons. Recent studies of hippocampal 'engram'cells, identified …
the level of populations of neurons. Recent studies of hippocampal 'engram'cells, identified …
Domain-selective and sex-dependent regulation of learning and memory in mice by GIRK channel activity in CA1 pyramidal neurons of the dorsal hippocampus
G protein-gated inwardly rectifying K+ (GIRK) channels mediate the postsynaptic inhibitory
effect of many neurotransmitters in the hippocampus and are implicated in neurological …
effect of many neurotransmitters in the hippocampus and are implicated in neurological …