Imaging faster neural dynamics with fast fMRI: A need for updated models of the hemodynamic response

JR Polimeni, LD Lewis - Progress in neurobiology, 2021 - Elsevier
Fast fMRI enables the detection of neural dynamics over timescales of hundreds of
milliseconds, suggesting it may provide a new avenue for studying subsecond neural …

[HTML][HTML] Functional MRI of brain physiology in aging and neurodegenerative diseases

JJ Chen - Neuroimage, 2019 - Elsevier
Brain aging and associated neurodegeneration constitute a major societal challenge as well
as one for the neuroimaging community. A full understanding of the physiological …

[HTML][HTML] Resting-state “physiological networks”

JE Chen, LD Lewis, C Chang, Q Tian, NE Fultz… - NeuroImage, 2020 - Elsevier
Slow changes in systemic brain physiology can elicit large fluctuations in fMRI time series,
which manifest as structured spatial patterns of temporal correlations between distant brain …

Imaging of the pial arterial vasculature of the human brain in vivo using high-resolution 7T time-of-flight angiography

S Bollmann, H Mattern, M Bernier, SD Robinson… - elife, 2022 - elifesciences.org
The pial arterial vasculature of the human brain is the only blood supply to the neocortex, but
quantitative data on the morphology and topology of these mesoscopic arteries (diameter 50 …

Decreased default mode network connectivity correlates with age-associated structural and cognitive changes

D Vidal-Piñeiro, C Valls-Pedret… - Frontiers in aging …, 2014 - frontiersin.org
Ageing entails cognitive and motor decline as well as brain changes such as loss of gray
(GM) and white matter (WM) integrity, neurovascular and functional connectivity alterations …

Comparing cerebrovascular reactivity measured using BOLD and cerebral blood flow MRI: The effect of basal vascular tension on vasodilatory and vasoconstrictive …

S Halani, JB Kwinta, AM Golestani, YB Khatamian… - Neuroimage, 2015 - Elsevier
Cerebrovascular reactivity (CVR) is an important metric of cerebrovascular health. While the
BOLD fMRI method in conjunction with carbon-dioxide (CO 2) based vascular manipulation …

Characterizing resting-state brain function using arterial spin labeling

JJ Chen, K Jann, DJJ Wang - Brain connectivity, 2015 - liebertpub.com
Arterial spin labeling (ASL) is an increasingly established magnetic resonance imaging
(MRI) technique that is finding broader applications in studying the healthy and diseased …

Biomarkers, designs, and interpretations of resting‐state fMRI in translational pharmacological research: A review of state‐of‐the‐art, challenges, and opportunities for …

N Khalili‐Mahani, SARB Rombouts… - Human brain …, 2017 - Wiley Online Library
A decade of research and development in resting‐state functional MRI (RSfMRI) has
opened new translational and clinical research frontiers. This review aims to bridge between …

Metabolic and vascular origins of the BOLD effect: Implications for imaging pathology and resting‐state brain function

CI Mark, EL Mazerolle, JJ Chen - Journal of Magnetic …, 2015 - Wiley Online Library
The blood oxygenation level‐dependent (BOLD) phenomenon has profoundly
revolutionized neuroscience, with applications ranging from normal brain development and …

Neural and metabolic basis of dynamic resting state fMRI

GJ Thompson - Neuroimage, 2018 - Elsevier
Resting state fMRI (rsfMRI) as a technique showed much initial promise for use in psychiatric
and neurological diseases where diagnosis and treatment were difficult. To realize this …