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Reconciling qualitative, abstract, and scalable modeling of biological networks
Predicting biological systems' behaviors requires taking into account many molecular and
genetic elements for which limited information is available past a global knowledge of their …
genetic elements for which limited information is available past a global knowledge of their …
Causal analysis of positive reaction systems
Cause/effect analysis of complex systems is instrumental in better understanding many
natural phenomena. Moreover, formal analysis requires the availability of suitable abstract …
natural phenomena. Moreover, formal analysis requires the availability of suitable abstract …
Complexity of the dynamics of reaction systems
Reaction systems are discrete dynamical systems inspired by bio-chemical processes,
whose dynamical behaviour is expressed by set-theoretic operations on finite sets. Reaction …
whose dynamical behaviour is expressed by set-theoretic operations on finite sets. Reaction …
Pure reaction automata
This work introduces the new class of pure reaction automata, as well as a new update
manner, called maximal reactive manner, that can also be applied to standard reaction …
manner, called maximal reactive manner, that can also be applied to standard reaction …
Fixed points and attractors of additive reaction systems
Reaction systems are discrete dynamical systems that simulate biological processes within
living cells through finite sets of reactants, inhibitors, and products. In this paper, we study …
living cells through finite sets of reactants, inhibitors, and products. In this paper, we study …
Model checking temporal properties of reaction systems
This paper defines a temporal logic for reaction systems (rsCTL). The logic is interpreted
over the models for the context restricted reaction systems that generalise standard reaction …
over the models for the context restricted reaction systems that generalise standard reaction …
[HTML][HTML] Evolving reaction systems
A Ehrenfeucht, J Kleijn, M Koutny… - Theoretical Computer …, 2017 - Elsevier
Reaction systems were introduced as a formal model of interactions between biochemical
reactions. These interactions, which are based on two mechanisms: facilitation and …
reactions. These interactions, which are based on two mechanisms: facilitation and …
Boolean networks and their dynamics: the impact of updates
Boolean networks are a mathematical model that has been widely used since decades in
the context of biological regulation networks' qualitative modelling. They consist in …
the context of biological regulation networks' qualitative modelling. They consist in …
Reaction systems: a model of computation inspired by the functioning of the living cell
Reaction systems are a model of computation inspired by the functioning of the living cell.
They formalize the interactions between biochemical reactions that form the basic …
They formalize the interactions between biochemical reactions that form the basic …
[HTML][HTML] Complexity of model checking for reaction systems
Reaction systems are a new mathematical formalism inspired by the living cell and driven by
only two basic mechanisms: facilitation and inhibition. As a modeling framework, they differ …
only two basic mechanisms: facilitation and inhibition. As a modeling framework, they differ …