Infectious Diseases Society of America 2024 guidance on the treatment of antimicrobial-resistant gram-negative infections
Abstract Background The Infectious Diseases Society of America (IDSA) is committed to
providing up-to-date guidance on the treatment of antimicrobial-resistant (AMR) infections …
providing up-to-date guidance on the treatment of antimicrobial-resistant (AMR) infections …
New β-lactam–β-lactamase inhibitor combinations
D Yahav, CG Giske, A Grāmatniece… - Clinical microbiology …, 2020 - Am Soc Microbiol
The limited armamentarium against drug-resistant Gram-negative bacilli has led to the
development of several novel β-lactam–β-lactamase inhibitor combinations (BLBLIs). In this …
development of several novel β-lactam–β-lactamase inhibitor combinations (BLBLIs). In this …
Infectious Diseases Society of America 2022 guidance on the treatment of extended-spectrum β-lactamase producing Enterobacterales (ESBL-E), carbapenem …
Abstract Background The Infectious Diseases Society of America (IDSA) is committed to
providing up-to-date guidance on the treatment of antimicrobial-resistant infections. The …
providing up-to-date guidance on the treatment of antimicrobial-resistant infections. The …
Interplay between β-lactamases and new β-lactamase inhibitors
Resistance to β-lactam antibiotics in Gram-negative bacteria is commonly associated with
production of β-lactamases, including extended-spectrum β-lactamases (ESBLs) and …
production of β-lactamases, including extended-spectrum β-lactamases (ESBLs) and …
Porins and small-molecule translocation across the outer membrane of Gram-negative bacteria
Gram-negative bacteria and their complex cell envelope, which comprises an outer
membrane and an inner membrane, are an important and attractive system for studying the …
membrane and an inner membrane, are an important and attractive system for studying the …
The “old” and the “new” antibiotics for MDR gram-negative pathogens: for whom, when, and how
The recent expansion of multidrug resistant and pan-drug-resistant pathogens poses
significant challenges in the treatment of healthcare associated infections. An important …
significant challenges in the treatment of healthcare associated infections. An important …
Antibiotic resistance breakers: current approaches and future directions
Infections of antibiotic-resistant pathogens pose an ever-increasing threat to mankind. The
investigation of novel approaches for tackling the antimicrobial resistance crisis must be part …
investigation of novel approaches for tackling the antimicrobial resistance crisis must be part …
Treatment of infections due to MDR Gram-negative bacteria
M Bassetti, M Peghin, A Vena, DR Giacobbe - Frontiers in medicine, 2019 - frontiersin.org
The treatment of multidrug-resistant Gram-negative bacteria (MDR-GNB) infections in
critically ill patients presents many challenges. Since an effective treatment should be …
critically ill patients presents many challenges. Since an effective treatment should be …
The Rise of Boron-Containing Compounds: Advancements in Synthesis, Medicinal Chemistry, and Emerging Pharmacology
Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …
Resistance to ceftazidime/avibactam, meropenem/vaborbactam and imipenem/relebactam in Gram-negative MDR bacilli: molecular mechanisms and susceptibility …
P Gaibani, T Giani, F Bovo, D Lombardo, S Amadesi… - Antibiotics, 2022 - mdpi.com
Multidrug resistance (MDR) represents a serious global threat due to the rapid global spread
and limited antimicrobial options for treatment of difficult-to-treat (DTR) infections sustained …
and limited antimicrobial options for treatment of difficult-to-treat (DTR) infections sustained …