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Brain connectomics: time for a molecular imaging perspective?
In the past two decades brain connectomics has evolved into a major concept in
neuroscience. However, the current perspective on brain connectivity and how it underpins …
neuroscience. However, the current perspective on brain connectivity and how it underpins …
The metabolic costs of cognition
Cognition and behavior are emergent properties of brain systems that seek to maximize
complex and adaptive behaviors while minimizing energy utilization. Different species …
complex and adaptive behaviors while minimizing energy utilization. Different species …
Functional PET/MRI reveals active inhibition of neuronal activity during optogenetic activation of the nigrostriatal pathway
S Haas, F Bravo, TM Ionescu… - Science …, 2024 - science.org
The dopaminergic system is a central component of the brain's neurobiological framework,
governing motor control and reward responses and playing an essential role in various …
governing motor control and reward responses and playing an essential role in various …
Task-evoked metabolic demands of the posteromedial default mode network are shaped by dorsal attention and frontoparietal control networks
External tasks evoke characteristic fMRI BOLD signal deactivations in the default mode
network (DMN). However, for the corresponding metabolic glucose demands both …
network (DMN). However, for the corresponding metabolic glucose demands both …
Dissociations between glucose metabolism and blood oxygenation in the human default mode network revealed by simultaneous PET-fMRI
The finding of reduced functional MRI (fMRI) activity in the default mode network (DMN)
during externally focused cognitive control has been highly influential to our understanding …
during externally focused cognitive control has been highly influential to our understanding …
1H magnetic resonance spectroscopic imaging of deuterated glucose and of neurotransmitter metabolism at 7 T in the human brain
Impaired glucose metabolism in the brain has been linked to several neurological disorders.
Positron emission tomography and carbon-13 magnetic resonance spectroscopic imaging …
Positron emission tomography and carbon-13 magnetic resonance spectroscopic imaging …
High-temporal resolution functional PET/MRI reveals coupling between human metabolic and hemodynamic brain response
Purpose Positron emission tomography (PET) provides precise molecular information on
physiological processes, but its low temporal resolution is a major obstacle. Consequently …
physiological processes, but its low temporal resolution is a major obstacle. Consequently …
[HTML][HTML] Whole-body metabolic connectivity framework with functional PET
The nervous and circulatory system interconnects the various organs of the human body,
building hierarchically organized subsystems, enabling fine-tuned, metabolically expensive …
building hierarchically organized subsystems, enabling fine-tuned, metabolically expensive …
Reconfiguration of functional brain networks and metabolic cost converge during task performance
The ability to solve cognitive tasks depends upon adaptive changes in the organization of
whole-brain functional networks. However, the link between task-induced network …
whole-brain functional networks. However, the link between task-induced network …
Dynamics of human serotonin synthesis differentially link to reward anticipation and feedback
Abstract Serotonin (5-HT) plays an essential role in reward processing, however, the
possibilities to investigate 5-HT action in humans during emotional stimulation are …
possibilities to investigate 5-HT action in humans during emotional stimulation are …