The evolving story of incretins (GIP and GLP‐1) in metabolic and cardiovascular disease: a pathophysiological update
MA Nauck, DR Quast, J Wefers… - Diabetes, Obesity and …, 2021 - Wiley Online Library
The incretin hormones glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐
like peptide‐1 (GLP‐1) have their main physiological role in augmenting insulin secretion …
like peptide‐1 (GLP‐1) have their main physiological role in augmenting insulin secretion …
[HTML][HTML] Glucagon-like peptide 1 (GLP-1)
TD Müller, B Finan, SR Bloom, D D'Alessio… - Molecular …, 2019 - Elsevier
Background The glucagon-like peptide-1 (GLP-1) is a multifaceted hormone with broad
pharmacological potential. Among the numerous metabolic effects of GLP-1 are the glucose …
pharmacological potential. Among the numerous metabolic effects of GLP-1 are the glucose …
Short-chain fatty acids in control of body weight and insulin sensitivity
The connection between the gut microbiota and the aetiology of obesity and cardiometabolic
disorders is increasingly being recognized by clinicians. Our gut microbiota might affect the …
disorders is increasingly being recognized by clinicians. Our gut microbiota might affect the …
Enteroendocrine cells: chemosensors in the intestinal epithelium
FM Gribble, F Reimann - Annual review of physiology, 2016 - annualreviews.org
The enteroendocrine system orchestrates how the body responds to the ingestion of foods,
employing a diversity of hormones to fine-tune a wide range of physiological responses both …
employing a diversity of hormones to fine-tune a wide range of physiological responses both …
Mechanisms underlying weight loss after bariatric surgery
The clinical efficacy of bariatric surgery has encouraged the scientific investigation of the gut
as a major endocrine organ. Manipulation of gastrointestinal anatomy through surgery has …
as a major endocrine organ. Manipulation of gastrointestinal anatomy through surgery has …
The glucagon-like peptides
TJ Kieffer, J Francis Habener - Endocrine reviews, 1999 - academic.oup.com
Glucagon-Like Peptides | Endocrine Reviews | Oxford Academic Skip to Main Content
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Advertisement Oxford Academic Journals Books Search Menu Information Account Menu …
Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down?
The incretin hormones gastric inhibitory polypeptide and especially glucagon-like peptide
(GLP) have an important physiological function in augmenting postprandial insulin …
(GLP) have an important physiological function in augmenting postprandial insulin …
Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients
MB Toft-Nielsen, MB Damholt… - The Journal of …, 2001 - academic.oup.com
To elucidate the causes of the diminished incretin effect in type 2 diabetes mellitus we
investigated the secretion of the incretin hormones, glucagon-like peptide-1 and glucose …
investigated the secretion of the incretin hormones, glucagon-like peptide-1 and glucose …
Regulation of energy balance by a gut–brain axis and involvement of the gut microbiota
PV Bauer, SC Hamr, FA Duca - Cellular and molecular life sciences, 2016 - Springer
Despite significant progress in understanding the homeostatic regulation of energy balance,
successful therapeutic options for curbing obesity remain elusive. One potential target for the …
successful therapeutic options for curbing obesity remain elusive. One potential target for the …
Tissue‐specific expression of the human receptor for glucagon‐like peptide‐I: brain, heart and pancreatic forms have the same deduced amino acid sequences
Y Wei, S Mojsov - FEBS letters, 1995 - Wiley Online Library
Glucagon‐like peptide‐I (GLP‐I), encoded by the glucagon gene and released from the gut
in response to nutrients, is a potent stimulator of glucose‐induced insulin secretion. In …
in response to nutrients, is a potent stimulator of glucose‐induced insulin secretion. In …