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Designing the next-generation clinical care pathway for Alzheimer's disease
The reconceptualization of Alzheimer's disease (AD) as a clinical and biological construct
has facilitated the development of biomarker-guided, pathway-based targeted therapies …
has facilitated the development of biomarker-guided, pathway-based targeted therapies …
[HTML][HTML] Precision and personalized medicine: how genomic approach improves the management of cardiovascular and neurodegenerative disease
Life expectancy has gradually grown over the last century. This has deeply affected
healthcare costs, since the growth of an aging population is correlated to the increasing …
healthcare costs, since the growth of an aging population is correlated to the increasing …
DementiaBank: Theoretical rationale, protocol, and illustrative analyses
Purpose: Dementia from Alzheimer's disease (AD) is characterized primarily by a significant
decline in memory abilities; however, language abilities are also commonly affected and …
decline in memory abilities; however, language abilities are also commonly affected and …
Precision public health in the era of genomics and big data
Precision public health (PPH) considers the interplay between genetics, lifestyle and the
environment to improve disease prevention, diagnosis and treatment on a population level …
environment to improve disease prevention, diagnosis and treatment on a population level …
Why loneliness interventions are unsuccessful: A call for precision health
Background: Loneliness has drawn increasing attention over the past few decades due to
rising recognition of its close connection with serious health issues, like dementia. Yet …
rising recognition of its close connection with serious health issues, like dementia. Yet …
A systems approach towards remote health-monitoring in older adults: Introducing a zero-interaction digital exhaust
Using connected sensing devices to remotely monitor health is a promising way to help
transition healthcare from a rather reactive to a more precision medicine oriented proactive …
transition healthcare from a rather reactive to a more precision medicine oriented proactive …
Components, prospects and challenges of personalized prevention
S Jaskulski, C Nuszbaum, KB Michels - Frontiers in Public Health, 2023 - frontiersin.org
Effective preventive strategies are urgently needed to address the rising burden of non-
communicable diseases such as cardiovascular disease and cancer. To date, most …
communicable diseases such as cardiovascular disease and cancer. To date, most …
[HTML][HTML] Cerebral Microbleeds in Different Brain Regions and Their Associations With the Digital Clock-Drawing Test: Secondary Analysis of the Framingham Heart …
Background Cerebral microbleeds (CMB) increase the risk for Alzheimer disease. Current
neuroimaging methods that are used to detect CMB are costly and not always accessible …
neuroimaging methods that are used to detect CMB are costly and not always accessible …
A novel online training programme for healthcare professionals caring for older adults
The proportion of older people in the world population is growing rapidly. Training and
retaining healthcare professionals in sufficient numbers in the field of ageing represents a …
retaining healthcare professionals in sufficient numbers in the field of ageing represents a …
[HTML][HTML] Digital clock drawing as an Alzheimer's disease susceptibility biomarker: associations with genetic risk score and APOE in older adults
Background Alzheimer's disease (AD) is the leading cause of dementia in older adults, but
most people are not diagnosed until significant neuronal loss has likely occurred along with …
most people are not diagnosed until significant neuronal loss has likely occurred along with …