A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrity

H Kadry, B Noorani, L Cucullo - Fluids and Barriers of the CNS, 2020 - Springer
The blood–brain barrier is playing a critical role in controlling the influx and efflux of
biological substances essential for the brain's metabolic activity as well as neuronal function …

Treatment and outcome of hemorrhagic transformation after intravenous alteplase in acute ischemic stroke: a scientific statement for healthcare professionals from the …

S Yaghi, JZ Willey, B Cucchiara, JN Goldstein… - Stroke, 2017 - ahajournals.org
Purpose—Symptomatic intracranial hemorrhage (sICH) is the most feared complication of
intravenous thrombolytic therapy in acute ischemic stroke. Treatment of sICH is based on …

Blood-brain barrier permeability and physical exercise

MA Małkiewicz, A Szarmach, A Sabisz… - Journal of …, 2019 - Springer
In this narrative review, a theoretical framework on the crosstalk between physical exercise
and blood-brain barrier (BBB) permeability is presented. We discuss the influence of …

Translational research in traumatic brain injury

D Laskowitz, G Grant - 2016 - books.google.com
Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …

Looking at the blood–brain barrier: molecular anatomy and possible investigation approaches

FL Cardoso, D Brites, MA Brito - Brain research reviews, 2010 - Elsevier
The blood–brain barrier (BBB) is a dynamic and complex interface between blood and the
central nervous system that strictly controls the exchanges between the blood and brain …

Implication of cerebral astrocytes in major depression: A review of fine neuroanatomical evidence in humans

LA O'Leary, N Mechawar - Glia, 2021 - Wiley Online Library
Postmortem investigations have implicated astrocytes in many neurological and psychiatric
conditions. Multiple brain regions from individuals with major depressive disorder (MDD) …

Biomarkers in traumatic brain injury (TBI): a review

A Dadas, J Washington, R Diaz-Arrastia… - … disease and treatment, 2018 - Taylor & Francis
Biomarkers can be broadly defined as qualitative or quantitative measurements that convey
information on the physiopathological state of a subject at a certain time point or disease …

The neuroinflammatory hypothesis of delirium

J Cerejeira, H Firmino, A Vaz-Serra… - Acta …, 2010 - Springer
Delirium is a neuropsychiatric syndrome characterized by a sudden and global impairment
in consciousness, attention and cognition. It is particularly frequent in elderly subjects with …

Consequences of repeated blood-brain barrier disruption in football players

N Marchi, JJ Bazarian, V Puvenna, M Janigro… - PloS one, 2013 - journals.plos.org
The acknowledgement of risks for traumatic brain injury in American football players has
prompted studies for sideline concussion diagnosis and testing for neurological deficits …

Fatty acid-binding proteins as plasma markers of tissue injury

MMAL Pelsers, WT Hermens, JFC Glatz - Clinica chimica acta, 2005 - Elsevier
BACKGROUND: One of the novel and promising plasma markers for detection of tissue
injury is the family of 15 kDa cytoplasmic fatty acid-binding proteins of which various tissue …