Important considerations regarding the widespread use of doxycycline chemoprophylaxis against sexually transmitted infections

FYS Kong, C Kenyon, M Unemo - Journal of Antimicrobial …, 2023 - academic.oup.com
Rates of sexually transmitted infections (STIs) continue to rise across the world and
interventions are essential to reduce their incidence. Past and recent studies have indicated …

[HTML][HTML] Seventy years of Chlamydia vaccine research–limitations of the past and directions for the future

S Phillips, BL Quigley, P Timms - Frontiers in microbiology, 2019 - frontiersin.org
Chlamydia is a major bacterial pathogen that infects humans, as well as a wide range of
animals, including marsupials, birds, cats, pigs, cattle, and sheep. Antibiotics are the only …

Human and pathogen factors associated with Chlamydia trachomatis-related infertility in women

S Menon, P Timms, JA Allan, K Alexander… - Clinical microbiology …, 2015 - Am Soc Microbiol
Chlamydia trachomatis is the most common bacterial sexually transmitted pathogen
worldwide. Infection can result in serious reproductive pathologies, including pelvic …

Azithromycin versus doxycycline for the treatment of genital chlamydia infection: a meta-analysis of randomized controlled trials

FYS Kong, SN Tabrizi, M Law… - Clinical Infectious …, 2014 - academic.oup.com
Background. There has been recent debate questioning the efficacy of azithromycin for the
treatment of urogenital chlamydia infection. We conducted a meta-analysis to compare the …

Mechanism of action, resistance, synergism, and clinical implications of azithromycin

M Heidary, A Ebrahimi Samangani… - Journal of clinical …, 2022 - Wiley Online Library
Background Azithromycin (AZM), sold under the name Zithromax, is classified as a
macrolide. It has many benefits due to its immunomodulatory, anti‐inflammatory, and …

Chlamydia trachomatis and Genital Mycoplasmas: Pathogens with an Impact on Human Reproductive Health

S Ljubin-Sternak, T Meštrović - Journal of pathogens, 2014 - Wiley Online Library
The most prevalent, curable sexually important diseases are those caused by Chlamydia
trachomatis (C. trachomatis) and genital mycoplasmas. An important characteristic of these …

Azithromycin antimicrobial resistance and genital Chlamydia trachomatis infection: duration of therapy may be the key to improving efficacy

PJ Horner - Sexually transmitted infections, 2012 - sti.bmj.com
A test of cure following treatment for uncomplicated cervical or urethral Chlamydia
trachomatis infection with either single dose azithromycin (1 g) or doxycyline (100mg twice …

Doxycycline in the management of sexually transmitted infections

H Peyriere, A Makinson, H Marchandin… - Journal of …, 2018 - academic.oup.com
Doxycycline is a second-generation tetracycline, available worldwide for half a century. It is
an inexpensive broad-spectrum antimicrobial agent largely used in the management of …

Treatment challenges for urogenital and anorectal Chlamydia trachomatis

FYS Kong, JS Hocking - BMC infectious diseases, 2015 - Springer
While true antimicrobial resistance to Chlamydia trachomatis is a rare occurrence, repeat
chlamydia infections continue to be reported following treatment with a single 1 g dose of …

Doxycycline Post-exposure Prophylaxis for bacterial sexually transmitted infections: The current landscape and future directions

LT Allan-Blitz, KH Mayer - Current HIV/AIDS Reports, 2025 - Springer
Doxycycline Post-Exposure Prophylaxis for Bacterial Sexually Transmitted Infections: The
Current Landscape and Future Directions | Current HIV/AIDS Reports Skip to main content …