Lipid polymer hybrid nanoparticles: a custom-tailored next-generation approach for cancer therapeutics
Lipid-based polymeric nanoparticles are the highly popular carrier systems for cancer drug
therapy. But presently, detailed investigations have revealed their flaws as drug delivery …
therapy. But presently, detailed investigations have revealed their flaws as drug delivery …
Recent development of aptamer conjugated chitosan nanoparticles as cancer therapeutics
There is a surge in demand for safe and targeted therapy against cancer as the conventional
treatment approach fails to reach the specific site. Chemotherapeutic agents are generally …
treatment approach fails to reach the specific site. Chemotherapeutic agents are generally …
[HTML][HTML] Chitosan-based nanoparticles with optimized parameters for targeted delivery of a specific anticancer drug—a comprehensive review
J Kurczewska - Pharmaceutics, 2023 - mdpi.com
Chitosan is a positively charged polysaccharide obtained through chitin deacetylation. It
belongs to a group of biodegradable, bioavailable, and non-toxic materials of natural origin; …
belongs to a group of biodegradable, bioavailable, and non-toxic materials of natural origin; …
Folate-engineered chitosan nanoparticles: next-generation anticancer nanocarriers
P Kesharwani, K Halwai, SK Jha, MH Al Mughram… - Molecular Cancer, 2024 - Springer
Chitosan nanoparticles (NPs) are well-recognized as promising vehicles for delivering
anticancer drugs due to their distinctive characteristics. They have the potential to enclose …
anticancer drugs due to their distinctive characteristics. They have the potential to enclose …
Delivery of natural products via polysaccharide-based nanocarriers for cancer therapy: a review on recent advances and future challenges
Y Jiang, C Yan, M Li, S Chen, Z Chen, L Yang… - International Journal of …, 2024 - Elsevier
Cancer, caused by uncontrolled proliferation of abnormal cells, has long been a global
public health issue. For decades, natural products have been proven to be an essential …
public health issue. For decades, natural products have been proven to be an essential …
Synergistic effects of quercetin-loaded CoFe2O4@Liposomes regulate DNA damage and apoptosis in MCF-7 cancer cells: based on biophysical magnetic …
S Elbeltagi, A Abdel shakor, H M. Alharbi… - Drug Development …, 2024 - Taylor & Francis
Introduction Breast cancer (BC) is the most common malignancy in women globally.
Significant progress has been made in develo** structural nanoparticles (NPs) and …
Significant progress has been made in develo** structural nanoparticles (NPs) and …
Folate decorated lipid chitosan hybrid nanoparticles of 5-fluorouracil for enhanced anticancer efficacy against colon cancer
The study aimed to develop folate decorated lipid chitosan hybrid nanoparticles for targeted
delivery of 5-fluorouracil in colon cancer by utilizing the overexpressed folate receptors on …
delivery of 5-fluorouracil in colon cancer by utilizing the overexpressed folate receptors on …
[HTML][HTML] Advances in the delivery of anticancer drugs by nanoparticles and chitosan-based nanoparticles
J Prieložná, V Mikušová, P Mikuš - International Journal of Pharmaceutics …, 2024 - Elsevier
Cancer is the leading cause of death globally, and conventional treatments have limited
efficacy with severe side effects. The use of nanotechnology has the potential to reduce the …
efficacy with severe side effects. The use of nanotechnology has the potential to reduce the …
Harnessing lipid polymer hybrid nanoparticles for enhanced oral bioavailability of thymoquinone: in vitro and in vivo assessments
The clinical application of phytochemicals such as thymoquinone (THQ) is restricted due to
their limited aqueous solubility and oral bioavailability. Develo** mucoadhesive …
their limited aqueous solubility and oral bioavailability. Develo** mucoadhesive …
[HTML][HTML] Colonic targeting insulin-loaded trimethyl chitosan nanoparticles coated pectin for oral delivery: In vitro and In vivo studies
Colon-targeted delivery offers several benefits for oral protein delivery, such as low
proteolytic enzyme activity, a natural pH environment, and extended residence time, which …
proteolytic enzyme activity, a natural pH environment, and extended residence time, which …