Health benefits and side effects of short-chain fatty acids

RG **ong, DD Zhou, SX Wu, SY Huang, A Saimaiti… - Foods, 2022 - mdpi.com
The gut microbiota and their metabolites could play an important role in health and diseases
of human beings. Short-chain fatty acids (SCFAs) are mainly produced by gut microbiome …

The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

Metagenomic analysis revealed the potential role of gut microbiome in gout

Y Chu, S Sun, Y Huang, Q Gao, X **e… - npj Biofilms and …, 2021 - nature.com
Emerging evidence indicates an association between gut microbiome and arthritis diseases
including gout. However, how and which gut bacteria affect host urate degradation and …

Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response

KH Antunes, JL Fachi, R de Paula, EF da Silva… - Nature …, 2019 - nature.com
Severe respiratory syncytial virus (RSV) infection is a major cause of morbidity and mortality
in infants< 2 years-old. Here we describe that high-fiber diet protects mice from RSV …

Parabacteroides produces acetate to alleviate heparanase-exacerbated acute pancreatitis through reducing neutrophil infiltration

Y Lei, L Tang, S Liu, S Hu, L Wu, Y Liu, M Yang… - Microbiome, 2021 - Springer
Background The endoglycosidase heparanase which degrades heparan sulfate
proteoglycans, exerts a pro-inflammatory mediator in various inflammatory disorders …

Inflammation in gout: mechanisms and therapeutic targets

AK So, F Martinon - Nature Reviews Rheumatology, 2017 - nature.com
The acute symptoms of gout are triggered by the inflammatory response to monosodium
urate crystals, mediated principally by macrophages and neutrophils. Innate immune …

[HTML][HTML] Butyrate protects mice from Clostridium difficile-induced colitis through an HIF-1-dependent mechanism

JL Fachi, J de Souza Felipe, LP Pral, BK da Silva… - Cell reports, 2019 - cell.com
Antibiotic-induced dysbiosis is a key factor predisposing intestinal infection by Clostridium
difficile. Here, we show that interventions that restore butyrate intestinal levels mitigate …

[HTML][HTML] Microbiota-gut-brain axis: modulator of host metabolism and appetite

M Van de Wouw, H Schellekens, TG Dinan… - The Journal of nutrition, 2017 - Elsevier
The gut harbors an enormous diversity of microbes that are essential for the maintenance of
homeostasis in health and disease. A growing body of evidence supports the role of this …

Limosilactobacillus fermentum JL-3 isolated from “Jiangshui” ameliorates hyperuricemia by degrading uric acid

Y Wu, Z Ye, P Feng, R Li, X Chen, X Tian, R Han… - Gut …, 2021 - Taylor & Francis
Recent studies into the beneficial effects of fermented foods have shown that this class of
foods are effective in managing hyperuricemia and gout. In this study, the uric acid (UA) …

The role of the intestine in the development of hyperuricemia

H Yin, N Liu, J Chen - Frontiers in immunology, 2022 - frontiersin.org
Gout is a common inflammatory arthritis caused by the deposition of sodium urate crystals in
the joints. Hyperuricemia is the fundamental factor of gout. The onset of hyperuricemia is …