[HTML][HTML] Antimicrobial peptides for combating drug-resistant bacterial infections

J Xuan, W Feng, J Wang, R Wang, B Zhang, L Bo… - Drug Resistance …, 2023 - Elsevier
The problem of drug resistance due to long-term use of antibiotics has been a concern for
years. As this problem grows worse, infections caused by multiple bacteria are expanding …

The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions

BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

Identification of antimicrobial peptides from the human gut microbiome using deep learning

Y Ma, Z Guo, B **a, Y Zhang, X Liu, Y Yu, N Tang… - Nature …, 2022 - nature.com
The human gut microbiome encodes a large variety of antimicrobial peptides (AMPs), but
the short lengths of AMPs pose a challenge for computational prediction. Here we combined …

Experimental demonstration of highly reliable dynamic memristor for artificial neuron and neuromorphic computing

SO Park, H Jeong, J Park, J Bae, S Choi - Nature Communications, 2022 - nature.com
Neuromorphic computing, a computing paradigm inspired by the human brain, enables
energy-efficient and fast artificial neural networks. To process information, neuromorphic …

Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

Identification of potent antimicrobial peptides via a machine-learning pipeline that mines the entire space of peptide sequences

J Huang, Y Xu, Y Xue, Y Huang, X Li, X Chen… - Nature Biomedical …, 2023 - nature.com
Systematically identifying functional peptides is difficult owing to the vast combinatorial
space of peptide sequences. Here we report a machine-learning pipeline that mines the …

CAMPR4: a database of natural and synthetic antimicrobial peptides

U Gawde, S Chakraborty, FH Waghu… - Nucleic Acids …, 2023 - academic.oup.com
There has been an exponential increase in the design of synthetic antimicrobial peptides
(AMPs) for its use as novel antibiotics. Synthetic AMPs are substantially enriched in residues …

Antimicrobial host defence peptides: functions and clinical potential

N Mookherjee, MA Anderson, HP Haagsman… - Nature reviews Drug …, 2020 - nature.com
Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …

DBAASP v3: database of antimicrobial/cytotoxic activity and structure of peptides as a resource for development of new therapeutics

M Pirtskhalava, AA Amstrong, M Grigolava… - Nucleic acids …, 2021 - academic.oup.com
Abstract The Database of Antimicrobial Activity and Structure of Peptides (DBAASP) is an
open-access, comprehensive database containing information on amino acid sequences …

Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications

P Tan, H Fu, X Ma - Nano Today, 2021 - Elsevier
Antibiotic resistance caused by antibiotic abuse, especially the emergence of multi-drug
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …