Light-based vat-polymerization bioprinting

R Levato, O Dudaryeva… - Nature Reviews …, 2023 - nature.com
Light-based vat-polymerization bioprinting enables computer-aided patterning of 3D cell-
laden structures in a point-by-point, layer-by-layer or volumetric manner, using vat (vats) …

Metabolic glycoengineering–exploring glycosylation with bioorthogonal chemistry

M Kufleitner, LM Haiber, V Wittmann - Chemical Society Reviews, 2023 - pubs.rsc.org
Glycans are involved in numerous biological recognition events. Being secondary gene
products, their labeling by genetic methods–comparable to GFP labeling of proteins–is not …

Dual-locked enzyme-activatable bioorthogonal fluorescence turn-on imaging of senescent cancer cells

X Wang, SS Liew, J Huang, Y Hu… - Journal of the American …, 2024 - ACS Publications
Bioorthogonal pretargeting optical imaging shows the potential for enhanced diagnosis and
prognosis. However, the bioorthogonal handles, known for being “always reactive”, may …

Theranostic fluorescent probes

A Sharma, P Verwilst, M Li, D Ma, N Singh… - Chemical …, 2024 - ACS Publications
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …

Engineering pyrrolysine systems for genetic code expansion and reprogramming

DL Dunkelmann, JW Chin - Chemical Reviews, 2024 - ACS Publications
Over the past 16 years, genetic code expansion and reprogramming in living organisms has
been transformed by advances that leverage the unique properties of pyrrolysyl-tRNA …

Chemical reporters for bacterial glycans: development and applications

N Banahene, HW Kavunja, BM Swarts - Chemical reviews, 2021 - ACS Publications
Bacteria possess an extraordinary repertoire of cell envelope glycans that have critical
physiological functions. Pathogenic bacteria have glycans that are essential for growth and …

The chemistry of heterocycles in the 21st century

VN Charushin, EV Verbitskiy, ON Chupakhin… - Uspekhi Khimii, 2024 - mathnet.ru
The chemistry of heterocyclic compounds has traditionally been and remains a bright area of
chemical science in Russia. This is due to the fact that many heterocycles find the widest …

Visible and near-infrared light-induced photoclick reactions

Y Fu, NA Simeth, W Szymanski… - Nature Reviews Chemistry, 2024 - nature.com
Photoclick reactions combine the advantages offered by light-driven processes, that is, non-
invasive and high spatiotemporal control, with classical click chemistry and have found …

Boosting Endogenous Copper (I) for Biologically Safe and Efficient Bioorthogonal Catalysis via Self-Adaptive Metal–Organic Frameworks

J Zhu, Y You, W Zhang, F Pu, J Ren… - Journal of the American …, 2023 - ACS Publications
As one of the most typical bioorthogonal reactions, the Cu (I)-catalyzed azide–alkyne 1, 3-
cycloaddition (CuAAC) reaction has received worldwide attention in intracellular …

Recent advances in bioorthogonal click chemistry for biomedical applications

A Battigelli, B Almeida, A Shukla - Bioconjugate Chemistry, 2022 - ACS Publications
Bioorthogonal click chemistry, first introduced in the early 2000s, has become one of the
most widely used approaches for designing advanced biomaterials for applications in tissue …