[HTML][HTML] Tree shrew (Tupaia belangeri) as a novel laboratory disease animal model

J **ao, R Liu, CS Chen - Zoological research, 2017 - ncbi.nlm.nih.gov
The tree shrew (Tupaia belangeri) is a promising laboratory animal that possesses a closer
genetic relationship to primates than to rodents. In addition, advantages such as small size …

Evolutionary biology of human hepatitis viruses

A Rasche, AL Sander, VM Corman, JF Drexler - Journal of Hepatology, 2019 - Elsevier
Hepatitis viruses are major threats to human health. During the last decade, highly diverse
viruses related to human hepatitis viruses were found in animals other than primates …

Animal models of hepatitis B virus infection–success, challenges, and future directions

Y Liu, S Maya, A Ploss - Viruses, 2021 - mdpi.com
Chronic hepatitis B virus (HBV) infection affects more than 250 million people worldwide,
which greatly increases the risk for terminal liver diseases, such as liver cirrhosis and …

Therapeutic antiviral effect of the nucleic acid polymer REP 2055 against persistent duck hepatitis B virus infection

F Noordeen, CA Scougall, A Grosse, Q Qiao… - PLoS …, 2015 - journals.plos.org
Previous studies have demonstrated that nucleic acid polymers (NAPs) have both entry and
post-entry inhibitory activity against duck hepatitis B virus (DHBV) infection. The inhibitory …

Tupaia belangeri as an experimental animal model for viral infection

K Tsukiyama-Kohara, M Kohara - Experimental animals, 2014 - jstage.jst.go.jp
Tupaias, or tree shrews, are small mammals that are similar in appearance to squirrels. The
morphological and behavioral characteristics of the group have been extensively …

Animal models for the study of hepatitis B virus pathobiology and immunity: past, present, and future

X Zhang, X Wang, M Wu, R Ghildyal… - Frontiers in microbiology, 2021 - frontiersin.org
Hepatitis B virus (HBV) infection is a global public health problem that plagues
approximately 240 million people. Chronic hepatitis B (CHB) often leads to liver …

Tree shrew as an emerging small animal model for human viral infection: a recent overview

MEH Kayesh, T Sanada, M Kohara… - Viruses, 2021 - mdpi.com
Viral infection is a global public health threat causing millions of deaths. A suitable small
animal model is essential for viral pathogenesis and host response studies that could be …

In Vivo Model Systems for Hepatitis B Virus Research

AM Ortega-Prieto, C Cherry, H Gunn… - ACS Infectious …, 2018 - ACS Publications
Hepatitis B virus (HBV) affects more than 257 million people globally, resulting in
progressively worsening liver disease, manifesting as fibrosis, cirrhosis, and hepatocellular …

Chronic hepatitis B virus infection and occurrence of hepatocellular carcinoma in tree shrews (Tupaia belangeri chinensis)

C Yang, P Ruan, C Ou, J Su, J Cao, C Luo, Y Tang… - Virology journal, 2015 - Springer
Abstract Background Hepatitis B virus (HBV) infection has been believed as a major cause
of hepatocellular carcinoma (HCC) for a long time, however, the evidences of which are …

[HTML][HTML] The tree shrew as a model for infectious diseases research

R Li, M Zanin, X **a, Z Yang - Journal of thoracic disease, 2018 - ncbi.nlm.nih.gov
Despite major advances in medicine, infectious diseases still pose a significant threat to
humanity. Mammalian models of disease have proved extremely useful in adding to the …