There is now overwhelming experimental and clinical evidence that atherosclerosis is a
chronic inflammatory disease. Lessons from genome-wide association studies, advanced in …

Glycerophospholipids represent a common class of lipids critically important for integrity of
cellular membranes. Oxidation of esterified unsaturated fatty acids dramatically changes …

Background—Inflammation has been closely linked to auto-immunogenic processes in
atherosclerosis. Plasmacytoid dendritic cells (pDCs) are specialized to produce type-I …

Objective—Atherosclerosis is an inflammatory disease. Autoimmune responses to low-
density lipoproteins (LDL) contribute to its progression, whereas immunization with LDL may …

Objectives: The present study evaluated the effect of phosphorylcholine (PC) immunization
on the extent of experimental atherosclerosis. Background: Immunization against oxidized …

Adaptive as well as innate immune responses contribute to the development of
atherosclerosis. Studies performed in experimental animals have revealed that some of …

Atherosclerosis is a chronic inflammatory disease. Many studies and observations suggest
that it could be caused by an immune reaction against autoantigens at the endothelial level …

Wigren M, Kolbus D, Dunér P, Ljungcrantz I, Söderberg I, Björkbacka H, Fredrikson GN,
Nilsson J.(Malmö University Hospital, Lund University; Malmö University, Malmo; Sweden) …

Background: Subsets of CD4+ T-cells have been proposed to serve differential roles in the
development of atherosclerosis. Some T-cell types are atherogenic (T-helper type 1), while …

Atherosclerosis is a chronic inflammatory disease of the artery wall. Adaptive immunity plays
a key role in the pathogenesis of atherosclerosis. Recently, modulation of the immune …