Gelsolin: the tail of a molecular gymnast

S Nag, M Larsson, RC Robinson, LD Burtnick - Cytoskeleton, 2013 - Wiley Online Library
Gelsolin superfamily members are Ca2+‐dependent, multidomain regulators of the actin
cytoskeleton. Calcium binding activates gelsolin by inducing molecular gymnastics (large …

Aldehyde dehydrogenase in solid tumors and other diseases: Potential biomarkers and therapeutic targets

J **a, S Li, S Liu, L Zhang - MedComm, 2023 - Wiley Online Library
The family of aldehyde dehydrogenases (ALDHs) contains 19 isozymes and is involved in
the oxidation of endogenous and exogenous aldehydes to carboxylic acids, which …

Methylomics analysis identifies epigenetically silenced genes and implies an activation of β‐catenin signaling in cervical cancer

YC Chen, RL Huang, YK Huang… - … journal of cancer, 2014 - Wiley Online Library
Using DNA methylation biomarkers in cancer detection is a potential direction in clinical
testing. Some methylated genes have been proposed for cervical cancer detection; …

HPV‐related methylation‐based reclassification and risk stratification of cervical cancer

S Yang, Y Wu, S Wang, P Xu, Y Deng… - Molecular …, 2020 - Wiley Online Library
Human papillomavirus (HPV) is a clear etiology of cervical cancer (CC). However, the
associations between HPV infection and DNA methylation have not been thoroughly …

Molecular targets of HPV oncoproteins: potential biomarkers for cervical carcinogenesis

AC de Freitas, EC Coimbra, MCG Leitão - Biochimica et Biophysica Acta …, 2014 - Elsevier
Cervical cancer is the second most common cancer among women worldwide and is
responsible for 275,000 deaths each year. Persistent infection with high-risk human …

ALDH1L1 and ALDH1L2 folate regulatory enzymes in cancer

SA Krupenko, NI Krupenko - Alcohol and Cancer: Proceedings of the Third …, 2018 - Springer
Epidemiological studies implicate excess ethanol ingestion as a risk factor for several
cancers and support the concept of a synergistic effect of chronic alcohol consumption and …

CGI-58: versatile regulator of intracellular lipid droplet homeostasis

L Yu, Y Li, A Grisé, H Wang - Lipid Transfer in Lipoprotein Metabolism and …, 2020 - Springer
Abstract Comparative gene identification-58 (CGI-58), also known as α/β-hydrolase domain-
containing 5 (ABHD5), is a member of a large family of proteins containing an α/β-hydrolase …

[HTML][HTML] DNA methylation changes in human papillomavirus-driven head and neck cancers

C Ekanayake Weeramange, KD Tang, S Vasani… - Cells, 2020 - mdpi.com
Disruption of DNA methylation patterns is one of the hallmarks of cancer. Similar to other
cancer types, human papillomavirus (HPV)-driven head and neck cancer (HNC) also …

The role of prickle proteins in vertebrate development and pathology

KA Radaszkiewicz, M Sulcova, E Kohoutková… - Molecular and Cellular …, 2024 - Springer
Prickle is an evolutionarily conserved family of proteins exclusively associated with planar
cell polarity (PCP) signalling. This signalling pathway provides directional and positional …

Genetic alterations in seborrheic keratoses

B Heidenreich, E Denisova, S Rachakonda… - …, 2017 - pmc.ncbi.nlm.nih.gov
Seborrheic keratoses are common benign epidermal lesions that are associated with
increased age and sun-exposure. Those lesions despite harboring multiple somatic …