Genetic variation and adaptation in Africa: implications for human evolution and disease
Because modern humans originated in Africa and have adapted to diverse environments,
African populations have high levels of genetic and phenotypic diversity. Thus, genomic …
African populations have high levels of genetic and phenotypic diversity. Thus, genomic …
Prevalence and changes of anemia among young children and women in 47 low-and middle-income countries, 2000-2018
J Sun, H Wu, M Zhao, CG Magnussen, B ** - EClinicalMedicine, 2021 - thelancet.com
Background Anemia remains a major public health issue, particularly for children and
women in low-and middle-income countries (LMICs). However, the current prevalence and …
women in low-and middle-income countries (LMICs). However, the current prevalence and …
Genetic variants of TLR4, including the novel variant, rs5030719, and related genes are associated with susceptibility to clinical malaria in African children
Background Malaria is a deadly disease caused by Plasmodium spp. Several blood
phenotypes have been associated with malarial resistance, which suggests a genetic …
phenotypes have been associated with malarial resistance, which suggests a genetic …
Population genetic evidence for positive and purifying selection acting at the human IFN-γ locus in Africa
MC Campbell, LT Smith, J Harvey - Genes & Immunity, 2019 - nature.com
Despite its critical role in the defense against microbial infection and tumor development,
little is known about the range of nucleotide and haplotype variation at IFN-γ, or the …
little is known about the range of nucleotide and haplotype variation at IFN-γ, or the …
Impact of natural selection due to malarial disease on human genetic variation
Malaria is an important selective pressure in modern human evolution. The dynamic
relationship between human hosts and Plasmodium parasites has left numerous “footprints” …
relationship between human hosts and Plasmodium parasites has left numerous “footprints” …
Influência de Variantes Genéticas em CD36, ICAM-1 e HBA na Variabilidade Fenotípica da Drepanocitose e da Malária
ISG Matos - 2024 - search.proquest.com
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical Page 1
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical Influência de …
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical Influência de …
[CITA][C] UNIVERSITY OF PENNSYLVANIA-PERELMAN SCHOOL OF MEDICINE
SA Tishkoff - Science Magazine, 2003