[HTML][HTML] Targeting the Warburg effect: A revisited perspective from molecular mechanisms to traditional and innovative therapeutic strategies in cancer

M Liao, D Yao, L Wu, C Luo, Z Wang, J Zhang… - … Pharmaceutica Sinica B, 2024 - Elsevier
Cancer reprogramming is an important facilitator of cancer development and survival, with
tumor cells exhibiting a preference for aerobic glycolysis beyond oxidative phosphorylation …

circRNA-miRNA-mRNA regulatory network in human lung cancer: an update

ZZ Liang, C Guo, MM Zou, P Meng, TT Zhang - Cancer cell international, 2020 - Springer
Circular RNAs, as hopeful diagnosis markers and therapeutic molecules, have been
studied, probed and applied into several diseases, such as cardiovascular diseases …

Circ3823 contributes to growth, metastasis and angiogenesis of colorectal cancer: involvement of miR-30c-5p/TCF7 axis

Y Guo, Y Guo, C Chen, D Fan, X Wu, L Zhao, B Shao… - Molecular cancer, 2021 - Springer
Background Colorectal cancer (CRC) is one of the most common malignant tumours. The
recurrence and metastasis of CRC seriously affect the survival rate of patients. Angiogenesis …

circTP63 functions as a ceRNA to promote lung squamous cell carcinoma progression by upregulating FOXM1

Z Cheng, C Yu, S Cui, H Wang, H **, C Wang… - Nature …, 2019 - nature.com
Circular RNAs (circRNAs) are identified as vital regulators in a variety of cancers. However,
the role of circRNA in lung squamous cell carcinoma (LUSC) remains largely unknown …

A circRNA–miRNA–mRNA network identification for exploring underlying pathogenesis and therapy strategy of hepatocellular carcinoma

D **ong, Y Dang, P Lin, D Wen, R He, D Luo… - Journal of translational …, 2018 - Springer
Abstract Background Circular RNAs (circRNAs) have received increasing attention in human
tumor research. However, there are still a large number of unknown circRNAs that need to …

Expression profiles, biological functions and clinical significance of circRNAs in bladder cancer

X Yang, T Ye, H Liu, P Lv, C Duan, X Wu, K Jiang, H Lu… - Molecular cancer, 2021 - Springer
Circular RNAs (circRNAs), which are single-stranded closed-loop RNA molecules lacking
terminal 5′ caps and 3′ poly (A) tails, are attracting increasing scientific attention for their …

CircECE1 activates energy metabolism in osteosarcoma by stabilizing c-Myc

S Shen, T Yao, Y Xu, D Zhang, S Fan, J Ma - Molecular cancer, 2020 - Springer
Background Osteosarcoma (OS) is the most common malignant bone tumor and has a poor
prognosis. The potential involvement of circular RNAs (circRNAs) in OS progression …

Biological roles and mechanisms of circular RNA in human cancers

Q Tang, SS Hann - OncoTargets and therapy, 2020 - Taylor & Francis
Circular RNA (circRNA) is an intriguing class of RNA with covalently closed-loop structure
and is highly stable and conservative. As new members of the ncRNAs, the function …

[HTML][HTML] CircRNAs in lung cancer-Biogenesis, function and clinical implication

C Wang, S Tan, J Li, WR Liu, Y Peng, W Li - Cancer letters, 2020 - Elsevier
Lung cancer is the leading cause of malignancy-related incidence and mortality worldwide.
Molecular mechanisms underlying tumorigenesis and development of lung cancer are still …

A novel circular RNA, circXPO1, promotes lung adenocarcinoma progression by interacting with IGF2BP1

Q Huang, H Guo, S Wang, Y Ma, H Chen, H Li… - Cell death & …, 2020 - nature.com
Studies have demonstrated that noncoding RNAs play important roles in various types of
cancer; however, noncoding RNAs derived from regions of genomic alterations have rarely …