Light sources and dosimetry techniques for photodynamic therapy

MM Kim, A Darafsheh - Photochemistry and photobiology, 2020 - Wiley Online Library
Effective treatment delivery in photodynamic therapy (PDT) requires coordination of the light
source, the photosensitizer, and the delivery device appropriate to the target tissue. Lasers …

Singlet oxygen photophysics: from liquid solvents to mammalian cells

M Bregnhøj, F Thorning, PR Ogilby - Chemical Reviews, 2024 - ACS Publications
Molecular oxygen, O2, has long provided a cornerstone for studies in chemistry, physics,
and biology. Although the triplet ground state, O2 (X3Σg–), has garnered much attention, the …

Nanoparticles in photodynamic therapy

SS Lucky, KC Soo, Y Zhang - Chemical reviews, 2015 - ACS Publications
Cancer accounted for 7.6 million deaths (around 13% of all deaths) worldwide in 2008.(1)
Almost 13 million cancer cases are newly diagnosed every year, and deaths are projected to …

Trends and targets in antiviral phototherapy

A Wiehe, JM O'Brien, MO Senge - Photochemical & Photobiological …, 2019 - pubs.rsc.org
Photodynamic therapy (PDT) is a well-established treatment option in the treatment of
certain cancerous and pre-cancerous lesions. Though best-known for its application in …

Imaging and photodynamic therapy: mechanisms, monitoring, and optimization

JP Celli, BQ Spring, I Rizvi, CL Evans… - Chemical …, 2010 - ACS Publications
The purpose of this review is to present the current state of the role of imaging in
photodynamic therapy (PDT). For the reader to fully appreciate the context of the discussions …

Singlet oxygen: there is indeed something new under the sun

PR Ogilby - Chemical Society Reviews, 2010 - pubs.rsc.org
Singlet oxygen, O2 (a1Δg), the lowest excited electronic state of molecular oxygen, has
been known to the scientific community for∼ 80 years. It has a characteristic chemistry that …

A comprehensive review on singlet oxygen generation in nanomaterials and conjugated polymers for photodynamic therapy in the treatment of cancer

N Singh, RS Gupta, S Bose - Nanoscale, 2024 - pubs.rsc.org
A key role in lessening humanity's continuous fight against cancer could be played by
photodynamic therapy (PDT), a minimally invasive treatment employed in the medical care …

The physics, biophysics and technology of photodynamic therapy

BC Wilson, MS Patterson - Physics in Medicine & Biology, 2008 - iopscience.iop.org
Photodynamic therapy (PDT) uses light-activated drugs to treat diseases ranging from
cancer to age-related macular degeneration and antibiotic-resistant infections. This paper …

Reactive oxygen nano-generators for cancer therapy

D Kalyane, D Choudhary, S Polaka, H Goykar… - Progress in Materials …, 2022 - Elsevier
Reactive oxygen species (ROS) play a vital role in the biological process. Interestingly,
based on the concentration of the ROS level, they can be beneficial or detrimental to tumor …

Far-red fluorescence probe for monitoring singlet oxygen during photodynamic therapy

S Kim, T Tachikawa, M Fujitsuka… - Journal of the American …, 2014 - ACS Publications
Singlet oxygen (1O2), molecular oxygen in the lowest excited state, has a critical role in the
cell-killing mechanism of photodynamic therapy (PDT). Although 1O2 phosphorescence …