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Microglial morphometric analysis: so many options, so little consistency
J Reddaway, PE Richardson, RJ Bevan… - Frontiers in …, 2023 - frontiersin.org
Quantification of microglial activation through morphometric analysis has long been a staple
of the neuroimmunologist's toolkit. Microglial morphological phenomics can be conducted …
of the neuroimmunologist's toolkit. Microglial morphological phenomics can be conducted …
Quantifying microglial morphology: an insight into function
TRF Green, RK Rowe - Clinical and experimental immunology, 2024 - academic.oup.com
Microglia are specialized immune cells unique to the central nervous system (CNS).
Microglia have a highly plastic morphology that changes rapidly in response to injury or …
Microglia have a highly plastic morphology that changes rapidly in response to injury or …
[HTML][HTML] Human microglial state dynamics in Alzheimer's disease progression
N Sun, MB Victor, YP Park, X ** in the adult mouse CNS using hierarchical clustering on principal components reveals regional heterogeneity but no sexual dimorphism
HRJ van Weering, TW Nijboer, ML Brummer… - Glia, 2023 - Wiley Online Library
Microglia are the resident macrophages of the central nervous system (CNS) and play a
pivotal role in immune surveillance and CNS homeostasis. Morphological transitions in …
pivotal role in immune surveillance and CNS homeostasis. Morphological transitions in …
Relationship between sex biases in gene expression and sex biases in autism and Alzheimer's disease
Background Sex differences in the brain may play an important role in sex-differential
prevalence of neuropsychiatric conditions. Methods In order to understand the …
prevalence of neuropsychiatric conditions. Methods In order to understand the …
Online conversion of reconstructed neural morphologies into standardized SWC format
Digital reconstructions provide an accurate and reliable way to store, share, model, quantify,
and analyze neural morphology. Continuous advances in cellular labeling, tissue …
and analyze neural morphology. Continuous advances in cellular labeling, tissue …
A P2RY12 deficiency results in sex-specific cellular perturbations and sexually dimorphic behavioral anomalies
Microglia are sexually dimorphic, yet, this critical aspect is often overlooked in
neuroscientific studies. Decades of research have revealed the dynamic nature of microglial …
neuroscientific studies. Decades of research have revealed the dynamic nature of microglial …
Development of a high-throughput pipeline to characterize microglia morphological states at a single-cell resolution
As rapid responders to their environments, microglia engage in functions that are mirrored
by their cellular morphology. Microglia are classically thought to exhibit a ramified …
by their cellular morphology. Microglia are classically thought to exhibit a ramified …