Translocation of proteins into mitochondria
W Neupert, JM Herrmann - Annu. Rev. Biochem., 2007 - annualreviews.org
Abstract About 10% to 15% of the nuclear genes of eukaryotic organisms encode
mitochondrial proteins. These proteins are synthesized in the cytosol and recognized by …
mitochondrial proteins. These proteins are synthesized in the cytosol and recognized by …
Mitochondrial protein import: from proteomics to functional mechanisms
Mitochondria contain∼ 1,000 different proteins, most of which are imported from the cytosol.
Two import pathways that direct proteins into the mitochondrial inner membrane and matrix …
Two import pathways that direct proteins into the mitochondrial inner membrane and matrix …
[HTML][HTML] Plant mRNAs move into a fungal pathogen via extracellular vesicles to reduce infection
S Wang, B He, H Wu, Q Cai, O Ramírez-Sánchez… - Cell Host & Microbe, 2024 - cell.com
Cross-kingdom small RNA trafficking between hosts and microbes modulates gene
expression in the interacting partners during infection. However, whether other RNAs are …
expression in the interacting partners during infection. However, whether other RNAs are …
Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins
Mitochondria import nuclear‐encoded precursor proteins to four different subcompartments.
Specific import machineries have been identified that direct the precursor proteins to the …
Specific import machineries have been identified that direct the precursor proteins to the …
[BOOK][B] The structure of biological membranes
PL Yeagle - 2004 - taylorfrancis.com
Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …
biochemistry. Now more than ever, it is essential to update our current understanding of …
[HTML][HTML] Mitochondrial protein import: common principles and physiological networks
Most mitochondrial proteins are encoded in the nucleus. They are synthesized as precursor
forms in the cytosol and must be imported into mitochondria with the help of different protein …
forms in the cytosol and must be imported into mitochondria with the help of different protein …
Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17
The presequence translocase of the inner mitochondrial membrane (TIM23 complex)
operates at a central junction of protein import. It accepts preproteins from the outer …
operates at a central junction of protein import. It accepts preproteins from the outer …
The protein import machinery of mitochondria
Most mitochondrial proteins are encoded by nuclear genes and then synthesized as
precursors on cytosolic ribosomes after which they must be imported into the organelle. The …
precursors on cytosolic ribosomes after which they must be imported into the organelle. The …
Map** protein interactions in the active TOM-TIM23 supercomplex
R Gomkale, A Linden, P Neumann… - Nature …, 2021 - nature.com
Nuclear-encoded mitochondrial proteins destined for the matrix have to be transported
across two membranes. The TOM and TIM23 complexes facilitate the transport of precursor …
across two membranes. The TOM and TIM23 complexes facilitate the transport of precursor …
Mitochondrial import and the twin-pore translocase
The mitochondrial inner membrane is rich in multispanning integral membrane proteins,
most of which mediate the vital transport of molecules between the matrix and the …
most of which mediate the vital transport of molecules between the matrix and the …