Mitochondria contain∼ 1,000 different proteins, most of which are imported from the cytosol.
Two import pathways that direct proteins into the mitochondrial inner membrane and matrix …

Abstract About 10% to 15% of the nuclear genes of eukaryotic organisms encode
mitochondrial proteins. These proteins are synthesized in the cytosol and recognized by …

Cross-kingdom small RNA trafficking between hosts and microbes modulates gene
expression in the interacting partners during infection. However, whether other RNAs are …

Over half of mitochondrial proteins are imported from the cytosol via the pre-sequence
pathway, controlled by the TOM complex in the outer membrane and the TIM23 complex in …

Most mitochondrial proteins are encoded in the nucleus. They are synthesized as precursor
forms in the cytosol and must be imported into mitochondria with the help of different protein …

Mitochondria import nuclear‐encoded precursor proteins to four different subcompartments.
Specific import machineries have been identified that direct the precursor proteins to the …

Mitochondria import nearly all of their approximately 1,000–2,000 constituent proteins from
the cytosol across their double-membrane envelope,,,–. Genetic and biochemical studies …

Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …

The presequence translocase of the inner mitochondrial membrane (TIM23 complex)
operates at a central junction of protein import. It accepts preproteins from the outer …

Nuclear-encoded mitochondrial proteins destined for the matrix have to be transported
across two membranes. The TOM and TIM23 complexes facilitate the transport of precursor …