Hypertension is a multifactorial disorder that probably results from the inheritance of a
number of susceptibility genes and involves multiple environmental determinants. Existing …

Hypertension is a serious global public health problem, affecting approximately 600 million
people worldwide. The lifetime risk of develo** the condition exceeds 50% in most …

Abstract Background/Aims: In humans, the kidneys regulate blood pressure by balancing
sodium concentrations. Fine-tuning of renal sodium reabsorption and excretion depends on …

report on the latest developments in the field with new information in basic as well as in
clinical sciences, Sodium in Health Diseases, covers both the physiology of sodium balance …

This review summarizes the current status of our knowledge about the role of
pharmacogenetic variation in response to diuretics and suggests future research topics for …

Background Tachycardia is commonly observed in hypertensive patients, predominantly
mediated by regulatory mechanisms integrated within the autonomic nervous system. The …

Essential hypertension (EH) is a polygenic and multifactorial disorder that results from
genetic and/or environmental factors (Lifton et al., 2001). This disease has no identifiable …

We sought to determine the effect of amiloride on blood pressure (BP) and the presence of
polymorphisms of the β-subunit of the epithelial sodium channel (ENaC) among …

The possible role of the β‐subunit of the epithelial sodium channel T594M polymorphism in
hypertensive disorders of pregnancy has not been examined. This study compared Black …

As sodium is the most abundant cation of the extracellular fluid (ECF) and sodium salts
account for the most important part of the osmotically active solutes in the plasma and …