Targeted alpha therapy: progress in radionuclide production, radiochemistry, and applications
This review outlines the accomplishments and potential developments of targeted alpha (α)
particle therapy (TAT). It discusses the therapeutic advantages of the short and highly …
particle therapy (TAT). It discusses the therapeutic advantages of the short and highly …
Radiolabeled nanomaterials for biomedical applications: radiopharmacy in the era of nanotechnology
Background Recent advances in nanotechnology have offered new hope for cancer
detection, prevention, and treatment. Nanomedicine, a term for the application of …
detection, prevention, and treatment. Nanomedicine, a term for the application of …
Radiometals in Imaging and Therapy: Highlighting Two Decades of Research
The present article highlights the important progress made in the last two decades in the
fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based …
fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based …
Alpha dose modeling in diffusing alpha‐emitters radiation therapy—Part I: single‐seed calculations in one and two dimensions
Abstract Background Diffusing alpha‐emitters Radiation Therapy (“DaRT”) is a new method,
presently in clinical trials, which allows treating solid tumors by alpha particles. DaRT relies …
presently in clinical trials, which allows treating solid tumors by alpha particles. DaRT relies …
The potentiation of anti-tumor immunity by tumor abolition with alpha particles, protons, or carbon ion radiation and its enforcement by combination with …
Y Keisari, I Kelson - Cells, 2021 - mdpi.com
The delivery of radiation therapy (RT) for cancer with intent to cure has been optimized and
standardized over the last 80 years. Both preclinical and clinical work emphasized the …
standardized over the last 80 years. Both preclinical and clinical work emphasized the …
Alpha dose modeling in diffusing alpha‐emitters radiation therapy. Part II: Lattice studies
Background Diffusing alpha‐emitters radiation therapy (“DaRT”) is a new method, presently
in clinical trials, which allows treating solid tumors by alpha particles. DaRT relies on …
in clinical trials, which allows treating solid tumors by alpha particles. DaRT relies on …
Atomic nanogenerators in targeted alpha therapies: Curie's legacy in modern cancer management
M Roscher, G Bakos, M Benešová - Pharmaceuticals, 2020 - mdpi.com
Atomic in vivo nanogenerators such as actinium-225, thorium-227, and radium-223 are of
increasing interest and importance in the treatment of patients with metastatic cancer …
increasing interest and importance in the treatment of patients with metastatic cancer …
Diffusing alpha-emitters radiation therapy in combination with temozolomide or bevacizumab in human glioblastoma multiforme xenografts
Y Nishri, M Vatarescu, I Luz, L Epstein… - Frontiers in …, 2022 - frontiersin.org
Glioblastoma multiforme (GBM) is at present an incurable disease with a 5-year survival rate
of 5.5%, despite improvements in treatment modalities such as surgery, radiation therapy …
of 5.5%, despite improvements in treatment modalities such as surgery, radiation therapy …
Diffusing alpha-emitters radiation therapy: approximate modeling of the macroscopic alpha particle dose of a point source
L Arazi - Physics in Medicine & Biology, 2020 - iopscience.iop.org
Diffusing alpha-emitters radiation therapy ('DaRT') is a new cancer-treatment modality,
which enables treating solid tumors by alpha particles. The treatment utilizes implantable …
which enables treating solid tumors by alpha particles. The treatment utilizes implantable …
RIG-1-like receptor activation synergizes with intratumoral alpha radiation to induce pancreatic tumor rejection, triple-negative breast metastases clearance, and …
V Domankevich, M Efrati, M Schmidt, E Glikson… - Frontiers in …, 2020 - frontiersin.org
Diffusing alpha-emitting radiation therapy (DaRT) employs intratumoral Ra-224-coated
seeds that efficiently destroy solid tumors by slowly releasing alpha-emitting atoms inside …
seeds that efficiently destroy solid tumors by slowly releasing alpha-emitting atoms inside …