Peroxisomes carry out various oxidative reactions that are tightly regulated to adapt to the
changing needs of the cell and varying external environments. Accordingly, they are …

The evolutionary emergence of organelles was a defining process in diversifying
biochemical reactions within the cell and enabling multicellularity. However …

Summary Tail-anchored (TA) proteins, defined by the presence of a single C-terminal
transmembrane domain (TMD), play critical roles throughout the secretory pathway and in …

Peroxisomes are ubiquitous organelles that proliferate under different physiological
conditions and can form de novo in cells that lack them. The endoplasmic reticulum (ER) has …

Lipid droplets (LDs) and peroxisomes are central players in cellular lipid homeostasis: some
of their main functions are to control the metabolic flux and availability of fatty acids (LDs and …

As a rule, organelles in eukaryotic cells can derive only from pre-existing organelles.
Peroxisomes are unique because they acquire their lipids and membrane proteins from the …

Peroxisomes can arise de novo from the endoplasmic reticulum (ER) via a maturation
process. Peroxisomes can also multiply by fission. We have investigated how these modes …

Peroxisomes are unique among the organelles of the endomembrane system. Unlike other
organelles that derive most if not all of their proteins from the ER (endoplasmic reticulum) …

Peroxisomes are highly dynamic intracellular organelles involved in a variety of metabolic
functions essential for the metabolism of long-chain fatty acids, d-amino acids, and many …

Mitochondria and peroxisomes are small ubiquitous organelles. They both play major roles
in cell metabolism, especially in terms of fatty acid metabolism, reactive oxygen species …