Cis-regulatory sequences in plants: their importance, discovery, and future challenges

RJ Schmitz, E Grotewold, M Stam - The plant cell, 2022 - academic.oup.com
The identification and characterization of cis-regulatory DNA sequences and how they
function to coordinate responses to developmental and environmental cues is of paramount …

Liquid-liquid phase separation in biology: mechanisms, physiological functions and human diseases

H Zhang, X Ji, P Li, C Liu, J Lou, Z Wang… - Science China Life …, 2020 - Springer
Cells are compartmentalized by numerous membrane-enclosed organelles and
membraneless compartments to ensure that a wide variety of cellular activities occur in a …

RNA-directed DNA methylation

RM Erdmann, CL Picard - PLoS genetics, 2020 - journals.plos.org
RNA-directed DNA methylation (RdDM) is a biological process in which non-coding RNA
molecules direct the addition of DNA methylation to specific DNA sequences. The RdDM …

Histone modifications regulate chromatin compartmentalization by contributing to a phase separation mechanism

L Wang, Y Gao, X Zheng, C Liu, S Dong, R Li, G Zhang… - Molecular cell, 2019 - cell.com
Eukaryotic chromosomes contain compartments of various functions, which are marked by
and enriched with specific histone modifications. However, the molecular mechanisms by …

Liquid-liquid phase separation of RBGD2/4 is required for heat stress resistance in Arabidopsis

S Zhu, J Gu, J Yao, Y Li, Z Zhang, W **a, Z Wang… - Developmental Cell, 2022 - cell.com
As sessile organisms, plants are highly sensitive to environmental stresses. In response to
stresses, globally repressed translation initiation leads to stress granule (SG) formation …

Post-translational modifications in liquid-liquid phase separation: a comprehensive review

J Li, M Zhang, W Ma, B Yang, H Lu, F Zhou… - Molecular …, 2022 - Springer
Liquid-liquid phase separation (LLPS) has received significant attention in recent biological
studies. It refers to a phenomenon that biomolecule exceeds the solubility, condensates and …

[HTML][HTML] RNA and liquid-liquid phase separation

Q Guo, X Shi, X Wang - Non-coding RNA Research, 2021 - Elsevier
Abstract Liquid-Liquid Phase Separation (LLPS) is a biological phenomenon that refers to
the components of similar properties form a droplets condensate in cells. These droplets …

The solid and liquid states of chromatin

JC Hansen, K Maeshima, MJ Hendzel - Epigenetics & Chromatin, 2021 - Springer
The review begins with a concise description of the principles of phase separation. This is
followed by a comprehensive section on phase separation of chromatin, in which we recount …

Phase separation in genome organization across evolution

M Feric, T Misteli - Trends in cell biology, 2021 - cell.com
Phase separation is emerging as a paradigm to explain the self-assembly and organization
of membraneless bodies in the cell. Recent advances show that this principle also extends …

Emerging mechanistic insights into the regulation of specialized metabolism in plants

LV Méteignier, HW Nützmann, N Papon, A Osbourn… - Nature plants, 2023 - nature.com
Plants biosynthesize a broad range of natural products through specialized and species-
specific metabolic pathways that are fuelled by core metabolism, together forming a …