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Oxidative stress and antioxidants in neurodegenerative disorders
EO Olufunmilayo, MB Gerke-Duncan, RMD Holsinger - Antioxidants, 2023 - mdpi.com
Neurodegenerative disorders constitute a substantial proportion of neurological diseases
with significant public health importance. The pathophysiology of neurodegenerative …
with significant public health importance. The pathophysiology of neurodegenerative …
[HTML][HTML] Nootropics as cognitive enhancers: types, dosage and side effects of smart drugs
M Malík, P Tlustoš - Nutrients, 2022 - mdpi.com
Nootropics, also known as “smart drugs” are a diverse group of medicinal substances whose
action improves human thinking, learning, and memory, especially in cases where these …
action improves human thinking, learning, and memory, especially in cases where these …
Ferroptosis and its role in diverse brain diseases
Ferroptosis is a recently identified, iron-regulated, non-apoptotic form of cell death. It is
characterized by cellular accumulation of lipid reactive oxygen species that ultimately leads …
characterized by cellular accumulation of lipid reactive oxygen species that ultimately leads …
Diverse compounds from pleuromutilin lead to a thioredoxin inhibitor and inducer of ferroptosis
E Llabani, RW Hicklin, HY Lee, SE Motika… - Nature …, 2019 - nature.com
The chemical diversification of natural products provides a robust and general method for
the creation of stereochemically rich and structurally diverse small molecules. The resulting …
the creation of stereochemically rich and structurally diverse small molecules. The resulting …
Oxytosis/ferroptosis—(Re-) emerging roles for oxidative stress-dependent non-apoptotic cell death in diseases of the central nervous system
Although nerve cell death is the hallmark of many neurological diseases, the processes
underlying this death are still poorly defined. However, there is a general consensus that …
underlying this death are still poorly defined. However, there is a general consensus that …
The chemical biology of ferroptosis in the central nervous system
RR Ratan - Cell chemical biology, 2020 - cell.com
Over the past five decades, thanatology has come to include the study of how individual
cells in our bodies die appropriately and inappropriately in response to physiological and …
cells in our bodies die appropriately and inappropriately in response to physiological and …
Oxidative stress, glutamate, and neurodegenerative disorders
JT Coyle, P Puttfarcken - Science, 1993 - science.org
There is an increasing amount of experimental evidence that oxidative stress is a causal, or
at least an ancillary, factor in the neuropathology of several adult neurodegenerative …
at least an ancillary, factor in the neuropathology of several adult neurodegenerative …
Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria
Hydrogen sulfide (H2S) is a synaptic modulator as well as a neuroprotectant in the brain. We
recently showed that H2S protects neurons from oxidative stress by increasing the levels of …
recently showed that H2S protects neurons from oxidative stress by increasing the levels of …
Hydrogen sulfide protects neurons from oxidative stress
Y Kimura, H Kimura - The FASEB journal, 2004 - Wiley Online Library
ABSTRACT Hydrogen sulfide (H2S), which is a well‐known toxic gas, is found in relatively
high concentrations in the brain. Although a neuromodulatory role of H2S has been …
high concentrations in the brain. Although a neuromodulatory role of H2S has been …
Natural compounds as medical strategies in the prevention and treatment of psychiatric disorders seen in neurological diseases
Psychiatric disorders are frequently encountered in many neurological disorders, such as
Alzheimer's and Parkinson diseases along with epilepsy, migraine, essential tremors, and …
Alzheimer's and Parkinson diseases along with epilepsy, migraine, essential tremors, and …