The hierarchy of the 3D genome

JH Gibcus, J Dekker - Molecular cell, 2013 - cell.com
Mammalian genomes encode genetic information in their linear sequence, but appropriate
expression of their genes requires chromosomes to fold into complex three-dimensional …

Chromosome territories and the global regulation of the genome

AJ Fritz, N Sehgal, A Pliss, J Xu… - Genes, Chromosomes …, 2019 - Wiley Online Library
Spatial positioning is a fundamental principle governing nuclear processes. Chromatin is
organized as a hierarchy from nucleosomes to Mbp chromatin domains (CD) or topologically …

Circulating nucleic acids damage DNA of healthy cells by integrating into their genomes

I Mittra, NK Khare, GV Raghuram, R Chaubal… - Journal of …, 2015 - Springer
Whether nucleic acids that circulate in blood have any patho-physiological functions in the
host have not been explored. We report here that far from being inert molecules, circulating …

[LIVRE][B] Electromagnetic fields in biology and medicine

MS Markov - 2015 - books.google.com
Electromagnetic field (EMF) modalities offer an alternative to the increasing use of
pharmaceutical products for therapeutic use. This book presents state-of-the-art EMF use in …

Microtubule dynamics drive enhanced chromatin motion and mobilize telomeres in response to DNA damage

J Lawrimore, TM Barry, RM Barry, AC York… - Molecular biology of …, 2017 - molbiolcell.org
Chromatin exhibits increased mobility on DNA damage, but the biophysical basis for this
behavior remains unknown. To explore the mechanisms that drive DNA damage–induced …

Life rhythm as a symphony of oscillatory patterns: electromagnetic energy and sound vibration modulates gene expression for biological signaling and healing

D Muehsam, C Ventura - Global advances in health and …, 2014 - journals.sagepub.com
All life exists within a sea of vibration, and rhythm is fundamental to all of life. Diurnal,
seasonal, lunar, and solar cycles, and the resonant electromagnetic field (EMF) oscillations …

[PDF][PDF] Biophysical mechanisms for nonthermal microwave effects

I Belyaev, MS Markov - 2015 - ec.europa.eu
Exposures to radio-frequency (RF, 3 kHz–300 GHz) electromagnetic radiation or
microwaves (MWs, 300 MHz–300 GHz) vary in many parameters: intensity (incident flux …

Electromagnetic interactions in regulations of cell behaviors and morphogenesis

G Sun, J Li, W Zhou, RG Hoyle, Y Zhao - Frontiers in Cell and …, 2022 - frontiersin.org
Emerging evidence indicates that the cellular electromagnetic field regulates the
fundamental physics of cell biology. The electromagnetic oscillations and synchronization of …

Fluorescence lifetime imaging for studying DNA compaction and gene activities

SM Levchenko, A Pliss, X Peng, PN Prasad… - Light: Science & …, 2021 - nature.com
Optical imaging is a most useful and widespread technique for the investigation of the
structure and function of the cellular genomes. However, an analysis of immensely …

Correlations of three-dimensional motion of chromosomal loci in yeast revealed by the double-helix point spread function microscope

MP Backlund, R Joyner, K Weis… - Molecular biology of the …, 2014 - molbiolcell.org
Single-particle tracking has been applied to study chromatin motion in live cells, revealing a
wealth of dynamical behavior of the genomic material once believed to be relatively static …