Traumatic brain injury (TBI) and Alzheimer's disease (AD) are devastating neurological
disorders, whose complex relationship is not completely understood. Cerebrovascular …

The Neurovascular Unit (NVU) is an important multicellular structure of the central nervous
system (CNS), which participates in the regulation of cerebral blood flow (CBF), delivery of …

Vascular dysfunction is a universal feature of aging and decreased cerebral blood flow has
been identified as an early event in the pathogenesis of Alzheimer9s disease (AD) …

Alzheimer's disease (AD) is the most prevalent form of dementia. Cerebrovascular
dysfunction is one of the earliest events in the pathogenesis of AD, as well as in vascular …

Background Alzheimer's disease (AD) is a pervasive age-related and highly heritable
neurodegenerative disorder but has no effective therapy. The complex cellular …

Impaired clearance in the Alzheimer's Disease (AD) brain is key in the formation of Aβ
parenchymal plaques and cerebrovascular deposits known as cerebral amyloid angiopathy …

Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the most prevalent
cause of dementia. The main cerebral histological hallmarks are represented by …

Amyloid-β (Aβ) pathology is known to promote chronic inflammatory responses in the brain.
It was thought previously that Aβ is only associated with Alzheimer's disease and Down …

Cerebral hemorrhage, a devastating subtype of stroke, is often caused by hypertension and
cerebral amyloid angiopathy (CAA). Pathological evidence of CAA is detected in …

Endothelial cells of the central nervous system over-express surface proteins during
neurological disorders, either as a cause, or a consequence, of the disease. Since the …