Synthesis and antiviral activities of neoechinulin B and its derivatives

K Nishiuchi, H Ohashi, K Nishioka… - Journal of Natural …, 2021 - ACS Publications
We have previously reported that neoechinulin B (1a), a prenylated indole diketopiperazine
alkaloid, shows antiviral activities against hepatitis C virus (HCV) via the inactivation of the …

Pharmacological effect of cepharanthine on SARS-CoV-2–induced disease in a Syrian hamster model

T Uematsu, R Takai-Todaka, K Haga… - Journal of Infection and …, 2025 - Elsevier
Abstract Background Coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a global public health threat …

Favipiravir and ivermectin show in vitro synergistic antiviral activity against SARS-CoV-2

K Jitobaom, C Boonarkart… - Acta …, 2023 - frontierspartnerships.org
Despite the urgent need for effective antivirals against SARS-CoV-2 to mitigate the
catastrophic impact of the COVID-19 pandemic, favipiravir and ivermectin are among the …

Antiviral activity of ciclesonide acetal derivatives blocking SARS-CoV-2 RNA replication

G Tsuji, S Nakajima, K Watashi, S Torii, R Suzuki… - Journal of …, 2022 - Elsevier
Ciclesonide (Cic) is approved as an inhalant for asthma and was clinically tested as a
candidate therapy for coronavirus disease 2019 (COVID-19). Its active metabolite Cic2 was …

The Bis (1, 2, 3, 4-tetrahydroisoquinoline) Alkaloids Cepharanthine and Berbamine Are Ligands of SK Channels

R Vitello, H Taouba, M Derand… - ACS Medicinal Chemistry …, 2024 - ACS Publications
Cepharanthine, a multitarget alkaloid which has recently been shown to be effective against
SARS-Cov-2, and berbamine, an alkaloid characterized as a calcium channel blocker, both …

[PDF][PDF] Nelfinavir: An Old Ally in the COVID-19 Fight? Microorganisms 2022, 10, 2471

A Gidari, S Sabbatini, C Pallotto, S Bastianelli… - 2022 - researchgate.net
After almost three years of the pandemic, Severe Acute Respiratory Syndrome Coronavirus
2 (SARS-CoV-2) is still spreading around the world, causing notable sanitary and social …