Ligand‐installed nanocarriers toward precision therapy
Abstract Development of drug‐delivery systems that selectively target neoplastic cells has
been a major goal of nanomedicine. One major strategy for achieving this milestone is to …
been a major goal of nanomedicine. One major strategy for achieving this milestone is to …
Magnetic particle imaging: current and future applications, magnetic nanoparticle synthesis methods and safety measures
C Billings, M Langley, G Warrington, F Mashali… - International Journal of …, 2021 - mdpi.com
Magnetic nanoparticles (MNPs) have a wide range of applications; an area of particular
interest is magnetic particle imaging (MPI). MPI is an imaging modality that utilizes …
interest is magnetic particle imaging (MPI). MPI is an imaging modality that utilizes …
Treatment of infarcted heart tissue via the capture and local delivery of circulating exosomes through antibody-conjugated magnetic nanoparticles
S Liu, X Chen, L Bao, T Liu, P Yuan, X Yang… - Nature biomedical …, 2020 - nature.com
The systemic biodistribution of endogenous extracellular vesicles is central to the
maintenance of tissue homeostasis. Here, we show that angiogenesis and heart function in …
maintenance of tissue homeostasis. Here, we show that angiogenesis and heart function in …
Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues
S Zanganeh, G Hutter, R Spitler, O Lenkov… - Nature …, 2016 - nature.com
Until now, the Food and Drug Administration (FDA)-approved iron supplement ferumoxytol
and other iron oxide nanoparticles have been used for treating iron deficiency, as contrast …
and other iron oxide nanoparticles have been used for treating iron deficiency, as contrast …
Cardiac cell–integrated microneedle patch for treating myocardial infarction
We engineered a microneedle patch integrated with cardiac stromal cells (MN-CSCs) for
therapeutic heart regeneration after acute myocardial infarction (MI). To perform cell-based …
therapeutic heart regeneration after acute myocardial infarction (MI). To perform cell-based …
Iron oxide nanoparticles in regenerative medicine and tissue engineering
RP Friedrich, I Cicha, C Alexiou - Nanomaterials, 2021 - mdpi.com
In recent years, many promising nanotechnological approaches to biomedical research
have been developed in order to increase implementation of regenerative medicine and …
have been developed in order to increase implementation of regenerative medicine and …
Light-Activated Gold–Selenium Core–Shell Nanocomposites with NIR-II Photoacoustic Imaging Performances for Heart-Targeted Repair
Y Sun, P Zhang, Y Li, Y Hou, C Yin, Z Wang, Z Liao… - ACS …, 2022 - ACS Publications
Mitochondrial dysfunction and oxidative damage represent important pathological
mechanisms of myocardial ischemia-reperfusion injury (MI/RI). Searching for potential …
mechanisms of myocardial ischemia-reperfusion injury (MI/RI). Searching for potential …
Targeted repair of heart injury by stem cells fused with platelet nanovesicles
Stem cell transplantation, as used clinically, suffers from low retention and engraftment of the
transplanted cells. Inspired by the ability of platelets to recruit stem cells to sites of injury on …
transplanted cells. Inspired by the ability of platelets to recruit stem cells to sites of injury on …
Targeted delivery of therapeutic agents to the heart
S Sahoo, T Kariya, K Ishikawa - Nature Reviews Cardiology, 2021 - nature.com
For therapeutic materials to be successfully delivered to the heart, several barriers need to
be overcome, including the anatomical challenges of access, the mechanical force of the …
be overcome, including the anatomical challenges of access, the mechanical force of the …
Artificially reprogrammed macrophages as tumor‐tropic immunosuppression‐resistant biologics to realize therapeutics production and immune activation
CX Li, Y Zhang, X Dong, L Zhang, MD Liu… - Advanced …, 2019 - Wiley Online Library
To engineer patient‐derived cells into therapy‐purposed biologics is a promising solution to
realize personalized treatments. Without using gene‐editing technology, a live cell‐typed …
realize personalized treatments. Without using gene‐editing technology, a live cell‐typed …