On the evolution of cellular senescence
The idea that senescent cells are causally involved in aging has gained strong support from
findings that the removal of such cells alleviates many age‐related diseases and extends …
findings that the removal of such cells alleviates many age‐related diseases and extends …
The relationship between telomere length and mortality risk in non-model vertebrate systems: a meta-analysis
Telomere length (TL) has become a biomarker of increasing interest within ecology and
evolutionary biology, and has been found to predict subsequent survival in some recent …
evolutionary biology, and has been found to predict subsequent survival in some recent …
[KNIHA][B] Mechanisms of life history evolution: the genetics and physiology of life history traits and trade-offs
Life history theory seeks to explain the evolution of the major features of life cycles by
analyzing the ecological factors that shape age-specific schedules of growth, reproduction …
analyzing the ecological factors that shape age-specific schedules of growth, reproduction …
Oxidative stress and hormesis in evolutionary ecology and physiology
D Costantini - A marriage between mechanistic and evolutionary …, 2014 - Springer
Research programmes on oxidative stress and hormesis are wide ranging. Biomedical and
toxicological sciences have traditionally centralised such research, but in the last years we …
toxicological sciences have traditionally centralised such research, but in the last years we …
Roles of telomere biology in cell senescence, replicative and chronological ageing
J Liu, L Wang, Z Wang, JP Liu - Cells, 2019 - mdpi.com
Telomeres with G-rich repetitive DNA and particular proteins as special heterochromatin
structures at the termini of eukaryotic chromosomes are tightly maintained to safeguard …
structures at the termini of eukaryotic chromosomes are tightly maintained to safeguard …
Organismal stress, telomeres and life histories
P Monaghan - Journal of Experimental Biology, 2014 - journals.biologists.com
Most organisms, including ourselves, are exposed to environmental stressors at various
points during life, and responses to such stressors have been optimised by evolution to give …
points during life, and responses to such stressors have been optimised by evolution to give …
Telomere biology in healthy aging and disease
H Oeseburg, RA de Boer, WH Van Gilst… - … -European Journal of …, 2010 - Springer
Aging is a biological process that affects most cells, organisms and species. Telomeres have
been postulated as a universal biological clock that shortens in parallel with aging in cells …
been postulated as a universal biological clock that shortens in parallel with aging in cells …
Do glucocorticoids mediate the link between environmental conditions and telomere dynamics in wild vertebrates? A review
Following the discoveries of telomeres and of their implications in terms of health and
ageing, there has been a growing interest into the study of telomere dynamics in wild …
ageing, there has been a growing interest into the study of telomere dynamics in wild …
Telomeres and life histories: the long and the short of it
P Monaghan - Annals of the New York Academy of Sciences, 2010 - Wiley Online Library
Telomeres are repetitive DNA sequences at the ends of eukaryote chromosomes. Telomere
loss limits the number of times cells can divide and is intimately involved in cell loss and …
loss limits the number of times cells can divide and is intimately involved in cell loss and …
The role of telomeres in the mechanisms and evolution of life-history trade-offs and ageing
AJ Young - … Transactions of the Royal Society B …, 2018 - royalsocietypublishing.org
Evolutionary biology and biomedicine have seen a surge of recent interest in the possibility
that telomeres play a role in life-history trade-offs and ageing. Here, I evaluate alternative …
that telomeres play a role in life-history trade-offs and ageing. Here, I evaluate alternative …