The unceasing circulation of SARS-CoV-2 leads to the continuous emergence of novel viral
sublineages. Here, we isolate and characterize XBB. 1, XBB. 1.5, XBB. 1.9. 1, XBB. 1.16. 1 …

Vaccine Effectiveness against Omicron XBB. 1.5 Subvariant A data survey of 1.8 million
people in Nebraska showed that XBB. 1.5 vaccine effectiveness was 52% against infection …

ABSTRACT Introduction The Omicron BA. 1 variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and subsequent sub-lineages exhibit partial escape from …

Abstract The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variant BA.
2.86 has over 30 mutations in spike compared with BA. 2 and XBB. 1.5, which raised the …

The spike glycoprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
continues to accumulate substitutions, leading to breakthrough infections of vaccinated …

A limitation of current SARS-CoV-2 vaccines is that they provide minimal protection against
infection with current Omicron subvariants,, although they still provide protection against …

Messenger RNA (mRNA) vaccines were highly effective against the ancestral SARS-CoV-2
strain, but the efficacy of bivalent mRNA boosters against XBB variants was substantially …

Background A global shift to bivalent mRNA vaccines is ongoing to counterbalance the
diminishing effectiveness of the original monovalent vaccines due to the evolution of SARS …

Three and a half years into the coronavirus disease 2019 (COVID-19) pandemic, the nature
and durability of protection against severe acute respiratory syndrome coronavirus 2 (SARS …

Waning antibody responses after COVID-19 vaccination combined with the emergence of
the SARS-CoV-2 Omicron lineage led to reduced vaccine effectiveness. As a …