Candidate biomarkers in psychiatric disorders: state of the field

A Abi‐Dargham, SJ Moeller, F Ali… - World …, 2023 - Wiley Online Library
The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …

Dangers of the chronic stress response in the context of the microbiota-gut-immune-brain axis and mental health: a narrative review

A Warren, Y Nyavor, A Beguelin, LA Frame - Frontiers in immunology, 2024 - frontiersin.org
More than 20% of American adults live with a mental disorder, many of whom are treatment
resistant or continue to experience symptoms. Other approaches are needed to improve …

Cognitive behavioral therapy for anxiety disorders in youth: efficacy, moderators, and new advances in predicting outcomes

S Pegg, K Hill, A Argiros, BO Olatunji… - Current Psychiatry …, 2022 - Springer
Abstract Purpose of Review This review integrates recent systematic reviews and meta-
analyses on the efficacy of cognitive behavioral therapy (CBT) for the treatment of anxiety …

Functional neural changes associated with psychotherapy in anxiety disorders–A meta-analysis of longitudinal fMRI studies

E Schrammen, K Roesmann, D Rosenbaum… - Neuroscience & …, 2022 - Elsevier
Successful psychotherapy for anxiety disorders is thought to be linked to functional neural
changes in prefrontal control areas and fear-related limbic regions. Thus, discovering such …

[HTML][HTML] Lack of evidence for predictive utility from resting state fMRI data for individual exposure-based cognitive behavioral therapy outcomes: A machine learning …

K Hilbert, J Böhnlein, C Meinke, AV Chavanne… - NeuroImage, 2024 - Elsevier
Data-based predictions of individual Cognitive Behavioral Therapy (CBT) treatment
response are a fundamental step towards precision medicine. Past studies demonstrated …

Neural mechanisms of acceptance-commitment therapy for obsessive-compulsive disorder: a resting-state and task-based fMRI study

SW Lee, S Kim, S Lee, HS Seo, H Cha… - Psychological …, 2024 - cambridge.org
BackgroundThere is growing evidence for the use of acceptance-commitment therapy (ACT)
for the treatment of obsessive-compulsive disorder (OCD). However, few fully implemented …

Neural circuit basis of pathological anxiety

TJ Akiki, J Jubeir, C Bertrand, L Tozzi… - Nature Reviews …, 2024 - nature.com
Anxiety disorders are the most prevalent mental health conditions worldwide. Unfortunately,
the understanding of the precise neurobiological mechanisms that underlie these disorders …

Resting-state connectivity and response to psychotherapy treatment in adolescents and adults with OCD: A randomized clinical trial

S Russman Block, LJ Norman, X Zhang… - American Journal of …, 2023 - psychiatryonline.org
Objective: Cortical-subcortical hyperconnectivity related to affective-behavioral integration
and cortical network hypoconnectivity related to cognitive control have been demonstrated …

Grey matter structural alterations in anxiety disorders: A voxel-based meta-analysis

H Liu, Z Hao, S Qiu, Q Wang, L Zhan, L Huang… - Brain Imaging and …, 2024 - Springer
Anxiety disorders (ADs) are a group of prevalent and destructive mental illnesses, but the
current understanding of their underlying neuropathology is still unclear. Employing voxel …

Association between resting-state connectivity patterns in the defensive system network and treatment response in spider phobia—a replication approach

EJ Leehr, FR Seeger, J Böhnlein, B Gathmann… - Translational …, 2024 - nature.com
Although highly effective on average, exposure-based treatments do not work equally well
for all patients with anxiety disorders. The identification of pre-treatment response-predicting …