The surprising discovery that the diatomic gas nitric oxide (NO) is generated by mammalian
cells and serves to regulate a multitude of physiological processes has continued to …

Glutathione (GSH) is the most abundant cellular tripeptide (L‐γ‐glutamate‐L‐cysteinyl‐
glycine) which is as critical as oxygen and water. This low molecular mass antioxidant has a …

S-glutathionylation and S-nitrosylation are reversible post-translational modifications on the
cysteine thiol groups of proteins, which occur in cells under physiological conditions and …

Nitric oxide and other redox active molecules such as oxygen free radicals provide essential
signalling in diverse neuronal functions, but their excess production and insufficient …

Protein S-nitrosation (SNO), a posttranslational modification (PTM) of cysteine (Cys)
residues elicited by nitric oxide (NO), regulates a wide range of protein functions. As a …

In our previous research, a series of phenylsulfonylfuroxan-based hydroxamates were
developed, among which compound 1 exhibited remarkable in vitro and in vivo antitumor …

Physical exercise has beneficial effect on anxiety disorders, but the underlying molecular
mechanism remains largely unknown. Here, it is demonstrated that physical exercise can …

It has become apparent that hydrogen sulfide (H 2 S), hydropersulfides (RSSH) and other
polysulfide species are all intimately linked biochemically. Indeed, at least some of the …

S-nitrosylation of proteins occurs as a consequence of the derivatization of cysteine thiols
with nitric oxide (NO) and is often associated with diseases and protein malfunction …

Abstract Development of oxidative/nitrosative stress associated with the activation of
oncogenic pathways results from the increase in the generation of reactive oxygen and …