Tandem Prins cyclization is a versatile method for the synthesis of fused/bridged/
spirotetrahydropyran scaffolds. Therefore, it has become a powerful tool for the …

In recent years, the field of organocatalysis has extensively explored the use of carbenium
ions for practical C− C bond forming reactions. In order to control the formation of new …

Chiral oxygen-containing heterocyclic compounds are of great interest for the development
of pharmaceuticals. Monoterpenes and their derivatives are naturally abundant precursors …

The Prins reaction is a very convenient synthetic platform for the preparation of oxygen-
containing heterocyclic compounds, especially tetrahydropyrans and tetrahydrofurans …

Tetrahydropyrans are common motifs in natural products and have now been constructed
with high stereocontrol through a three‐component allylboration‐Prins reaction sequence …

A concise total synthesis of (−)-exiguolide has been completed in an overall 2.8% yield over
20 steps in the longest linear path. The key strategies involve (1) Prins cyclization …

An unprecedented access to strained tetracyclic bridgehead alkenes by reaction of easily
accessible ortho‐alkynylarylaldehydes with conjugated dienes is described. The process …

A general and practical method for the preparation of trans-2-substituted-4-halopiperidines
and cis-2-substituted-4-halotetrahydropyrans is reported. Using 5 mol% of AlCl3 as the …

The total synthesis of (+)-cryptocaryol A was achieved in 20 steps from (R)-glycidol. The key
steps were a Prins cyclization/reductive cleavage sequence to construct the C5–C11 polyol …

Microwave-assisted organic transformation (MAOR) is presently gaining wide popularity in
the field of organic synthesis. The conventional heating technique is gradually being …