Stem cells in clinical practice: applications and warnings

D Lodi, T Iannitti, B Palmieri - Journal of Experimental & Clinical Cancer …, 2011 - Springer
Stem cells are a relevant source of information about cellular differentiation, molecular
processes and tissue homeostasis, but also one of the most putative biological tools to treat …

The role of stem cell transplantation for chronic myelogenous leukemia in the 21st century

AJ Barrett, S Ito - Blood, The Journal of the American Society of …, 2015 - ashpublications.org
The introduction of tyrosine kinase inhibitors (TKIs), a treatment of chronic myelogenous
leukemia (CML), has largely replaced curative strategies based on allogeneic stem cell …

Allogeneic hematopoietic stem cell transplantation for chronic myeloid leukemia in Europe 2006: transplant activity, long-term data and current results. An analysis by …

A Gratwohl, R Brand, J Apperley, C Crawley… - …, 2006 - haematologica.org
The introduction of imatinib mesylate has changed attitudes towards hematopoietic stem cell
transplantation (HSCT) for chronic myeloid leukemia (CML). Information on the current use …

Outcomes of reduced-intensity transplantation for chronic myeloid leukemia: an analysis of prognostic factors from the Chronic Leukemia Working Party of the EBMT

C Crawley, R Szydlo, M Lalancette, A Bacigalupo… - Blood, 2005 - ashpublications.org
This study reports outcomes of allogeneic hematopoietic stem cell transplantation with
reduced-intensity conditioning (RIC) in 186 patients with chronic myeloid leukemia (CML) …

Chronic myeloid leukemia: current application of cytogenetics and molecular testing for diagnosis and treatment

A Tefferi, GW Dewald, ML Litzow, J Cortes… - Mayo Clinic …, 2005 - Elsevier
Chronic myeloid leukemia provides an illustrative disease model for both molecular
pathogenesis of cancer and rational drug therapy. Chronic myeloid leukemia is a clonal …

Therapeutic choices in patients with Ph-positive CML living in Mexico in the tyrosine kinase inhibitor era: SCT or TKIs?

GJ Ruiz-Argüelles, LC Tarin-Arzaga… - Bone marrow …, 2008 - nature.com
A total of 72 patients with Ph-positive CML in first chronic phase were followed during a 6-
year period in two different institutions in México. Among them, 22 were given a reduced …

The cure of chronic myeloid leukemia: are we there yet?

T Saikia - Current Oncology Reports, 2018 - Springer
Purpose of Review A large number of chronic myeloid leukemia (CML) patients receiving
tyrosine kinase inhibitors (TKIs) can now enjoy a deep molecular control of the disease and …

Hematopoietic cell transplantation from HLA-identical sibling donors after low-dose radiation-based conditioning for treatment of CML

FR Kerbauy, R Storb, U Hegenbart, T Gooley, J Shizuru… - Leukemia, 2005 - nature.com
A total of 24 patients (median age 58; range, 27–71 years) with chronic myeloid leukemia
(CML) in first chronic (CP1)(n= 14), second chronic (n= 4), or accelerated phase (n= 6) who …

The early referral for reduced-intensity stem cell transplantation in patients with Ph1 (+) chronic myelogenous leukemia in chronic phase in the imatinib era: results of …

GJ Ruiz-Argüelles, D Gomez-Almaguer… - Bone marrow …, 2005 - nature.com
Using a reduced-intensity stem cell transplantation (RIST) schedule, 24 patients with
Philadelphia (Ph1)(+) chronic myelogenous leukemia (CML) in first chronic phase (CP) were …

Pushing the envelope—nonmyeloablative and reduced intensity preparative regimens for allogeneic hematopoietic transplantation

SR **ali, RE Champlin - Bone marrow transplantation, 2015 - nature.com
Allogeneic hematopoietic cell transplantation (HCT) was originally developed to allow
delivery of myeloablative doses of chemotherapy and radiotherapy. With better …